Results 61 to 70 of about 23,131 (216)

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, Volume 38, Issue 60, 27 October 2026.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Data from: Immune challenges decrease biliverdin concentration in the spleen of Northern Bobwhite Quail, Colinus virginianus

, 2018
Most antioxidants have multiple functions; in addition to minimizing oxidative damage, many antioxidants have immune-modulating properties. For example, biliverdin is produced in the liver and spleen from the breakdown of heme, and has putative immune ...
Butler, Michael W., Hines, Justin K., Homsher, Melissa P., Astor, Michael T.   +3 more
core   +1 more source

Metabolic Functions of Biliverdin IXβ Reductase in Redox-Regulated Hematopoietic Cell Fate

Antioxidants, 2023
Cytoprotective heme oxygenases derivatize heme to generate carbon monoxide, ferrous iron, and isomeric biliverdins, followed by rapid NAD(P)H-dependent biliverdin reduction to the antioxidant bilirubin.
Wadie F. Bahou, Natalia Marchenko, Natasha M. Nesbitt   +2 more
doaj   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, Volume 13, Issue 59, 23 October 2026.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Production of biliverdin by biotransformation of exogenous heme using recombinant Pichia pastoris cells

Bioresources and Bioprocessing
Biliverdin, a bile pigment hydrolyzed from heme by heme oxygenase (HO), serves multiple functions in the human body, including antioxidant, anti-inflammatory, and immune response inhibitory activities.
Jianfeng Mei, Yanchao Han, Shihang Zhuang, Zhikai Yang, Yu Yi, Guoqing Ying   +5 more
doaj   +1 more source

Cordycepin Regulates the Nrf2/Hmox1 Signaling Pathway to Inhibit Ferroptosis and Improve AKI‐CKD

Cell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT Cordycepin (COR) exerts pharmacological effects in various diseases, yet its role in tissue repair following acute kidney injury (AKI) remains to be fully elucidated. This study aimed to investigate whether COR delays the progression from acute kidney injury to chronic kidney disease (AKI‐CKD) and to explore its underlying mechanisms.
Luming Xi, Mengqi Bai, Junhu Li, Zhibo Zhao, Xiaoshuang Zhou   +4 more
wiley   +1 more source

Integrating Transcriptomic and Proteome Analysis to Understand Muscle Qualities and Related Regulatory Factors of Holstein Beef Under Transportation Stress

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
In Holstein steers subjected to 15 h of long‐distance transportation, beef exhibited marked differences in meat quality, myofibrillar structure, and flavor components compared with cattle slaughtered without prior transport. These differences included significantly increased shear force, water loss rate, and drip loss, shortened sarcomere length, and ...
Zhaomin Lei, Siyu Cheng, Ruixin Yang, Jinping Shi, Zemin Li, Wangjing Liu   +5 more
wiley   +1 more source

Biliverdin protects rat livers from ischemia/reperfusion injury

, 2003
Objective. To explore putative cytoprotective functions of biliverdin during hepatic ischemia/reperfusion (I/R) injury in rat ...
Kupiec-Weglinski, J. W., Fondevila, C., Busuttil, R. W., Lassman, C., Carmody, I., Bach, F. H., Katori, M.   +6 more
core   +1 more source

Carbon Monoxide: A Context-Dependent Regulator of the Stress Axis

Biomolecules
Carbon monoxide (CO) is a gasotransmitter generated by heme oxygenase (HO) isoforms during heme catabolism. The inducible HO-1 produces CO under conditions of redox imbalance, such as oxidative stress and inflammation.
Cesare Mancuso, Rosaria Santangelo
doaj   +1 more source

Subarachnoid Hemorrhage Increases Level of Heme Oxygenase-1 and Biliverdin Reductase in the Choroid Plexus

Frontiers in Cellular Neuroscience, 2020
Subarachnoid hemorrhage is a specific, life-threatening form of hemorrhagic stroke linked to high morbidity and mortality. It has been found that the choroid plexus of the brain ventricles forming the blood-cerebrospinal fluid barrier plays an important ...
Peter Solár, Peter Solár, Peter Solár, Václav Brázda, Václav Brázda, Shahaf Levin, Alemeh Zamani, Radim Jančálek, Radim Jančálek, Petr Dubový, Marek Joukal   +10 more
doaj   +1 more source