Results 31 to 40 of about 7,014 (156)
The interesting application of bile salt hydrolase enzyme is reduction of cholesterol in serum and amelioration lipid profile. While uricase enzyme can be applied to convert insoluble uric acid to be soluble form and excrete from the body. Probiotics are
Atipat Yasiri, Supawadee Seubsasana
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Development of Bile Salt-Resistant Leuconostoc citreum by Expression of Bile Salt Hydrolase Gene
Probiotic bacteria must have not only tolerance against bile salt but also no genes for antibiotic resistance. Leuconostoc citreum is a dominant lactic acid bacterium in various fermented foods, but it is not regarded as a probiotic because it lacks bile salt resistance. Therefore, we aimed to construct a bile salt-resistant L.
Seung Kee, Cho +7 more
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Selection of Lactobacillus with High Bile Salt Hydrolase Activity and Its preventive and therapeutic effects against Neonatal Jaundice in Rats [PDF]
This study aimed to select Lactobacillus with high bile salt hydrolase (BSH) and to explore its protective role against neonatal jaundice. The LBS selective medium supplemented with 25 U/mL nystatin was used to screen and identify Lactobacillus strains ...
ZHANG Huimin, LI Binbin, PAN Xiaohua, SUN Jia
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Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe
Background Lactobacillus mucosae DPC 6426 has previously demonstrated potentially cardio-protective properties, in the form of dyslipidaemia and hypercholesterolemia correction in an apolipoprotein-E deficient mouse model. This study aims to characterise
Paul M. Ryan +10 more
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Effects of Structural Changes in Bile Salt Hydrolase Enzyme on Biocatalytic Efficiency and Activation Energy at Working pH and Temperature Conditions [PDF]
Microbial bile salt hydrolases (BSHs) catalyse the hydrolysis of glycine and taurine-linked bile salts in the small intestine of humans. Achieving the effects of structural changes in BSH molecules on biocatalytic efficiency (kcat/Km) and activation ...
Yakup Ermurat +3 more
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Forty-eight lactic acid bacteria (LAB) isolated from fermented mussels in Thailand were evaluated for their probiotic properties, bile salt hydrolase (BSH), cholesterol assimilation and immunomodulatory effects.
Engkarat Kingkaew +4 more
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Recently the roles of gut microbiota are highly regarded in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). The intestinal bacteria regulate the metabolism of bile acids depending on bile salt hydrolase (BSH), 7-dehydroxylation ...
Zhonglin Li +3 more
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Role of gut microbiota in the development of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease characterized by hepatic steatosis in the absence of other causes, such as chronic alcohol consumption, that cause secondary hepatic fat accumulation.
Xuemei Wang, Jialin Xia, Changtao Jiang
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Bile salt hydrolase/aminoacyltransferase shapes the microbiome
Abstract Bile acids (BAs) are steroid detergents in bile that contribute to the absorption of fats and fat-soluble vitamins while shaping the gut microbiome due to their antimicrobial properties. Recently, a novel mechanism of BA metabolism by the gut microbiota was identified involving conjugation with various amino acids.
Douglas Guzior +6 more
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Background Bile salt hydrolase plays an important role in bile acid-mediated signaling pathways, which regulate lipid absorption, glucose metabolism, and energy homeostasis.
Ziwei Song +10 more
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