Results 161 to 170 of about 40,709 (257)

Conjugated Linoleic Acid‐Enriched Fermented Dairy Modulates Microbiota and Metabolites to Alleviate MASLD: Insights From Multi‐Omics and Causal Mediation Analysis

open access: yesFood Frontiers, Volume 7, Issue 5, September 2026.
In a 120‐day randomized trial, CLA‐enriched fermented dairy remodeled the gut microbiota and rewired host metabolic pathways in patients with MASLD. These changes were accompanied by reductions in ALT, total cholesterol, creatinine, and hs‐CRP, supporting a microbiota‐mediated dietary strategy for metabolic and liver health.
Fei Mi   +13 more
wiley   +1 more source

Effect of bile salts on intestinal epithelial function in gilthead seabream (Sparus aurata). [PDF]

open access: yesFish Physiol Biochem
Fuentes J   +5 more
europepmc   +1 more source

Bile Salts Promote ToxR Regulon Activation during Growth under Virulence-Inducing Conditions. [PDF]

open access: yesInfect Immun, 2021
Bina TF   +5 more
europepmc   +1 more source

Whole Wheat Flour Components Intervention Against Lead Toxicity: Impacts on Metal Bioavailability and Protection of the Intestinal Epithelial Barrier

open access: yesFood Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT Consumption of whole wheat flour promotes lead excretion, yet the functional components reducing lead bioavailability and their protective mechanisms remain unclear. To identify these components and to validate whether their mechanism is related to protection of the intestinal barrier, this study established an in vitro model combining ...
Zhiyin Xiao   +7 more
wiley   +1 more source

<i>Clostridioides difficile</i> colonization is not mediated by bile salts and utilizes Stickland fermentation of proline in an <i>in vitro</i> model. [PDF]

open access: yesmSphere
Huang X   +12 more
europepmc   +1 more source

A Norovirus Uses Bile Salts To Escape Antibody Recognition While Enhancing Receptor Binding. [PDF]

open access: yesJ Virol, 2021
Williams AN   +6 more
europepmc   +1 more source

Improving Proteolysis‐Targeting Chimera Delivery by Targeting Key Biomarkers in Tumor Endocytosis Pathways

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen   +3 more
wiley   +1 more source

Role of Bile Acids and Bile Salts in Acute Pancreatitis: From the Experimental to Clinical Studies. [PDF]

open access: yesPancreas, 2021
Tran QT   +13 more
europepmc   +1 more source

Cyclins and Cyclin‐Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng   +9 more
wiley   +1 more source

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