Results 141 to 150 of about 45,839 (288)

Bio‐guided fractionation of (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid from Abelmoschus sagittifolius root as a potent α‐glucosidase inhibitor: An integrated in vitro and in silico study

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Abelmoschus sagittifolius stands out as a valuable medicinal source for developing functional food targeting type 2 diabetes. This study investigated the α‐glucosidase inhibitory potential of an active fraction obtained from A. sagittifolius roots (ASR), enriched in (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid (OA), using both enzyme ...
Nguyen Phuong Mai   +3 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Examining the effects of bile salts on Shigella flexneri pathogenesis

open access: yes, 2023
The Shigella species are Gram-negative facultative anaerobes that are the causative agents of millions of shigellosis infections annually. Shigellosis infections are characterized by watery and/or bloody diarrhea, abdominal cramps, and dehydration.
Bodnar, Ashley
core  

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao   +4 more
wiley   +1 more source

Surface hydrophilicity promotes bacterial twitching motility

open access: yesmSphere
Twitching motility is a form of bacterial surface translocation powered by the type IV pilus (T4P). It is frequently analyzed by interstitial colony expansion between agar and the polystyrene surfaces of petri dishes.
Megan T. O'Hara   +4 more
doaj   +1 more source

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source

Toxicology of bile salts in animals.

open access: yes, 2012
[[abstract]]In Asia, ingestion of animal bile is believed to improve health, but poisoning cases often occur. The composition of the bile varies with animal species, and is important in the diagnosis of hepatobiliary diseases.
謝宥諒;Hsieh, You-Liang
core  

Effect of bile salts on bacterial growth.

open access: yes, 2014
The increment of optical density after 48 h of incubation for each isolate in media containing different bile salts concentrations are displayed. Box-and-whisker plots represent each bile salt concentration (0.1, 0.25 and 0.5%).
Carla Foditsch (408566)   +6 more
core   +1 more source

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