Results 131 to 140 of about 40,709 (257)

GLP‐1 Receptor Agonists and Weight Loss: A Critical Review of Mechanisms

open access: yesObesity Reviews, EarlyView.
ABSTRACT GLP‐1 receptor agonist medications have the potential to promote marked weight loss, but maximal and sustained benefit may be compromised by poor compliance and cessation of use. Development of next‐generation medications that address current obstacles to effective use and development of effective adjunct treatments will benefit from better ...
Giorgia Rutigliani   +8 more
wiley   +1 more source

Can bile salts affect the contractile oesophageal activity associated with gastroesophageal reflux disease? [PDF]

open access: yesWorld J Gastroenterol
Gadelha KKL   +4 more
europepmc   +1 more source

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

open access: yesObesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid   +22 more
wiley   +1 more source

Acidic bile salts induce APE1-dependent PRDX2 activation to drive oxaliplatin resistance via ferroptosis inhibition. [PDF]

open access: yesRedox Biol
Chen L   +13 more
europepmc   +1 more source

A Crazy Idea: Ibn Sīnā on Hylomorphism, the Elements, Mixture and Evolutionary Processes

open access: yesTheoria, EarlyView.
ABSTRACT Ibn Sīnā (c. 973‐1037), the Avicenna of Latin fame, developed a unique theory of the elements and their status in mixtures that severely challenged the views of earlier natural philosophers and in its turn was severely challenged by later Latin Schoolmen in the West.
Jon McGinnis
wiley   +1 more source

Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver. [PDF]

open access: yesCell Res, 2022
Liu H   +8 more
europepmc   +1 more source

Pathophysiology of the gut–eye axis in a Sjögren's disease‐like dry eye mouse model: An exploratory evaluation of dietary heat‐treated Enterococcus faecalis FK‐23

open access: yesExperimental Physiology, EarlyView.
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto   +3 more
wiley   +1 more source

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