Autoinducer-2 and bile salts induce c-di-GMP synthesis to repress the T3SS via a T3SS chaperone. [PDF]
Li S +13 more
europepmc +1 more source
Disordered Bile Acid Metabolism in Alcohol‐Related Hepatitis
Serum conjugated primary bile acids accumulate in alcohol‐related hepatitis due to downregulation of hepatocyte bile acid transporters. Hepatocyte growth factor is elevated in alcohol‐related hepatitis and downregulates BSEP expression. This detrimentally affects the hepatoprotective adaptive reduction in NTCP/increase in BSEP seen in cholestasis ...
Luke D. Tyson +22 more
wiley +1 more source
Comparative effects of bile salts and free bile acids on intestinal health of grouper (<i>Epinephelus</i> spp.) fed a high cottonseed protein concentrate diet. [PDF]
Wang F +6 more
europepmc +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Drug delivery systems incorporating bile salts: advancements since the conception of bilosomes. [PDF]
Obeid MA +5 more
europepmc +1 more source
Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine. [PDF]
Wen J +10 more
europepmc +1 more source
A cell‐based high‐throughput screening system utilizing the luminescent probe LISA‐103 was developed to monitor γ‐glutamylcyclotransferase (GGCT) activity in cancer cells. Through this assay, plumbagin was identified as a novel GGCT inhibitor that induces cell cycle arrest and suppresses cancer cell growth. ABSTRACT γ‐Glutamylcyclotransferase (GGCT) is
Keiko Taniguchi +10 more
wiley +1 more source
Clostridioides difficile colonization is not mediated by bile salts and utilizes Stickland fermentation of proline in an in vitro model. [PDF]
Huang X +12 more
europepmc +1 more source
Microbiota-Liver-Bile Salts Axis, a Novel Mechanism Involved in the Contrasting Effects of Sodium Selenite and Selenium-Nanoparticle Supplementation on Adipose Tissue Development in Adolescent Rats. [PDF]
Ojeda ML +6 more
europepmc +1 more source

