Results 201 to 210 of about 399,922 (291)

Bile Salts Promote ToxR Regulon Activation during Growth under Virulence-Inducing Conditions. [PDF]

Infect Immun, 2021
Bina TF, Kunkle DE, Bina XR, Mullett SJ, Wendell SG, Bina JE.   +5 more
europepmc   +1 more source

HAY'S REACTION FOR BILE SALTS [PDF]

BMJ, 1902
A P, Beddard, M S, Pembrey
openaire   +2 more sources

Mesenchymal stromal cell‐derived extracellular vesicles improve islet β‐cell metabolic function via miRNA‐mediated regulation of Ankyrin‐B expression

Diabetic Medicine, EarlyView.
Abstract Aims Mesenchymal stromal‐cell‐derived extracellular vesicles (MSC‐EVs) improve islet function, which may be mediated in part through the delivery of microRNAs (miRNAs) to β‐cells. To investigate the underlying mechanisms, we identified the most abundant MSC‐EV miRNAs, their relative transfer to β‐cells and the extent to which Ankyrin‐B (Ank2 ...
Tzu‐Wen Hong, Ryea Arora, Rosie Sullivan, Zekun Lyu, William T. Blackstone Whines, Lydia F. Daniels Gatward, Ella L. Hubber, Tien‐Chi Huang, Aileen J. F. King, Shanta J. Persaud, Peter M. Jones   +10 more
wiley   +1 more source

A Norovirus Uses Bile Salts To Escape Antibody Recognition While Enhancing Receptor Binding. [PDF]

J Virol, 2021
Williams AN, Sherman MB, Smith HQ, Taube S, Pettitt BM, Wobus CE, Smith TJ.   +6 more
europepmc   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

<i>Clostridioides difficile</i> colonization is not mediated by bile salts and utilizes Stickland fermentation of proline in an <i>in vitro</i> model. [PDF]

mSphere
Huang X, Johnson AE, Brehm JN, Do TVT, Auchtung TA, McCullough HC, Lerma AI, Haidacher SJ, Hoch KM, Horvath TD, Sorg JA, Haag AM, Auchtung JM.   +12 more
europepmc   +1 more source

Molecular dynamics simulations elucidate the misfolding mechanisms of secretion‐defective pancreatic lipase variants

The FEBS Journal, EarlyView.
Misfolding mutations in pancreatic lipase have been identified as potential contributors of chronic pancreatitis, an inflammatory disease of the human pancreas. Here, we describe the effect of these misfolding mutations on pancreatic lipase structure using molecular dynamics simulations and structural modeling.
Gyula Hoffka, András Szabó
wiley   +1 more source

Structural modifications and augmented affinity for bile salts in enzymatically denatured egg white. [PDF]

Food Chem X
Liu C, Wu Y, Jin G, Xu B, Mei L.
europepmc   +1 more source

Cyclin‐dependent kinase 4/6 (CDK4/6) inhibitor‐induced hepatotoxicity and its resolution: a study of seven cases

Histopathology, EarlyView.
CDK4/6 inhibitor‐induced liver injury represents a clinically significant and histologically distinctive form of drug‐induced hepatotoxicity, most commonly encountered with ribociclib. The predominant pattern is severe acute hepatocellular injury, frequently accompanied by lymphocytic cholangitis, a combination that, in the appropriate clinical context,
Sunayana Misra, Lisa Centeno, Dupinder Singh, Romil Saxena, Rifat Mannan   +4 more
wiley   +1 more source

Proteomic Analysis Reveals the Phenotypic Heterogeneity and Tolerance Mechanisms of Halophilic <i>Vibrio parahaemolyticus</i> Under Dual Stress of Low Salinity and Bile Salts in the Human Intestine. [PDF]

Biomolecules
Guo Y, Yang B, Zhou X, Gong Z, Wang E, Pan Y, Zhao Y, Liu H.   +7 more
europepmc   +1 more source