Results 211 to 220 of about 40,709 (257)
Some of the next articles are maybe not open access.
Bile Salt Metabolism:II. Bile Salts and Disease
Australian and New Zealand Journal of Medicine, 1977Alterations of bile salt metabolism have been shown in numerous diseases. Liver damage results in elevated serum bile salt concentrations which may be useful as a sensitive index of hepatocellular disease. Changes in the relative proportions of the individual bile salts in serum occur with cholestasis.
C B, Campbell, A E, Cowen
openaire +2 more sources
Annual Review of Physiology, 2002
▪ Abstract Bile salts are the major organic solutes in bile and undergo extensive enterohepatic circulation. Hepatocellular bile salt uptake is mediated predominantly by the Na+-taurocholate cotransport proteins Ntcp (rodents) and NTCP (humans) and by the Na+-independent organic anion-transporting polypeptides Oatp1, Oatp2, and Oatp4 (rodents) and ...
Meier, Peter J., Stieger, B.
openaire +3 more sources
▪ Abstract Bile salts are the major organic solutes in bile and undergo extensive enterohepatic circulation. Hepatocellular bile salt uptake is mediated predominantly by the Na+-taurocholate cotransport proteins Ntcp (rodents) and NTCP (humans) and by the Na+-independent organic anion-transporting polypeptides Oatp1, Oatp2, and Oatp4 (rodents) and ...
Meier, Peter J., Stieger, B.
openaire +3 more sources
Bile Salt Roles in Bile-Salt-Stimulated Lipase Activity
Journal of Pediatric Gastroenterology and Nutrition, 1986SummaryThe hydrolysis of 4‐nitrophenylacetate and phenylsalicylate, catalyzed by human milk lipase in the presence of a range of concentrations of sodium cholate, has been measured at pH 7.3 and 37.5°C, and maximum activity was observed for both substrates at 1 mmole/ dm−3 bile salt.
C J, O'Connor, P, Walde, R G, Wallace
openaire +2 more sources
Current Gastroenterology Reports, 2005
Alterations in bile acid metabolism and in the enterohepatic circulation are often associated with chronic diarrhea and should be considered when more common causes of chronic diarrhea have been excluded. Bile acid diarrhea most often occurs in disease or resection of the terminal ileum, in which there is increased exposure of the colonic mucosa to ...
Bruce W, Robb, Jeffrey B, Matthews
openaire +2 more sources
Alterations in bile acid metabolism and in the enterohepatic circulation are often associated with chronic diarrhea and should be considered when more common causes of chronic diarrhea have been excluded. Bile acid diarrhea most often occurs in disease or resection of the terminal ileum, in which there is increased exposure of the colonic mucosa to ...
Bruce W, Robb, Jeffrey B, Matthews
openaire +2 more sources
Nature, 1969
BILE salts are detergent-like molecules which occur widely in living systems. The dihydroxy and trihydroxy bile salts have an extraordinary ability to solubilize insoluble lipids such as phospholipids1–5, monoglycerides6 and long chain alkyl alcohols7.
D M, Small, W, Admirand
openaire +2 more sources
BILE salts are detergent-like molecules which occur widely in living systems. The dihydroxy and trihydroxy bile salts have an extraordinary ability to solubilize insoluble lipids such as phospholipids1–5, monoglycerides6 and long chain alkyl alcohols7.
D M, Small, W, Admirand
openaire +2 more sources
2013
Bile salts play a crucial role in hepatobiliary and intestinal homeostasis and digestion. The liver synthesizes primary bile salts from cholesterol. Enzymatic modifications during their enterohepatic circulation lead to the formation of secondary and tertiary bile salts.
Maillette de Buy Wenniger, Lucas +2 more
openaire +1 more source
Bile salts play a crucial role in hepatobiliary and intestinal homeostasis and digestion. The liver synthesizes primary bile salts from cholesterol. Enzymatic modifications during their enterohepatic circulation lead to the formation of secondary and tertiary bile salts.
Maillette de Buy Wenniger, Lucas +2 more
openaire +1 more source
Digestive and Liver Disease, 2010
Bile salts have a crucial role in hepatobiliary and intestinal homeostasis and digestion. Primary bile salts are synthesized by the liver from cholesterol, and may be modified by the intestinal flora to form secondary and tertiary bile salts. Bile salts are efficiently reabsorbed from the intestinal lumen to undergo enterohepatic circulation.
Maillette de Buy Wenniger, Lucas +1 more
openaire +3 more sources
Bile salts have a crucial role in hepatobiliary and intestinal homeostasis and digestion. Primary bile salts are synthesized by the liver from cholesterol, and may be modified by the intestinal flora to form secondary and tertiary bile salts. Bile salts are efficiently reabsorbed from the intestinal lumen to undergo enterohepatic circulation.
Maillette de Buy Wenniger, Lucas +1 more
openaire +3 more sources
Bile salts and hydrodynamics of bile formation
Journal of Hepatology, 1989We report a novel method to assess bile secretory pressure using a Statham pressure transducer. The studies were performed in vivo in male Sprague-Dawley rats under pentobarbital anesthesia. Maximal secretory pressure averaged 21.8 +/- 1.1 (S.D.) cmH2O.
Cotting J, Reichen J
openaire +3 more sources
Bile Salt Structure and Phase Equilibria in Aqueous Bile Salt and Bile Salt-Lecithin Systems
Hepatology, 1984The hydrophilic-hydrophobic balance of bile salt monomers can be readily quantified by their elution sequence during reverse-phase high-performance liquid chromatography. Such studies have demonstrated that subtle variations in bile salt structure have profound effects on the hydrophilic-hydrophobic balance of this important ...
openaire +2 more sources
Effects of bile salts on bile formation in rabbits
Life Sciences, 1986The effects of different species of bile salts: deoxycholate, taurochenodeoxycholate, ursodeoxycholate, glycodeoxycholate, tauroursodeoxycholate, chenodeoxycholate and cholate (DCA, TCDC, UDCA, GDCA, TUDC, CDCA, CA) on bile secretion were examined in anesthetized rabbits using two different infusion routes.
K, Miyasaka, K, Kitani
openaire +2 more sources