Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Lactobacillus Kefir M20 Adaptation to Bile Salts: A Novel Pathway for Cholesterol Reduction. [PDF]
Ma C +6 more
europepmc +1 more source
Hydrophobic Bile Salts Induce Pro-Fibrogenic Proliferation of Hepatic Stellate Cells through PI3K p110 Alpha Signaling. [PDF]
Zimny S +8 more
europepmc +1 more source
Alamandine/MrgD pathway modulates gut–bone marrow axis in ageing
Abstract Background and Purpose Ageing is associated with colon epithelial barrier disruption and up‐regulation of myelopoiesis in the bone marrow (BM). Alamandine (Ala) and MrgD are novel members of the renin angiotensin system (RAS). This study tested the hypothesis that Ala restores the colon epithelial barrier integrity in ageing via modulating gut–
Kishore Chittimalli +6 more
wiley +1 more source
Effects of high stocking density on the growth performance, intestinal health and bile salts composition of broiler chickens. [PDF]
Dong Y +16 more
europepmc +1 more source
On the mechanism of the cholesterol lowering ability of soluble dietary fibers: Interaction of some bile salts with pectin, alginate, and chitosan studied by isothermal titration calorimetry. [PDF]
Massa M, Compari C, Fisicaro E.
europepmc +1 more source
Expanding the Biochemical Phenotype of ReNU Syndrome: A Case Report
This report detailed the clinical findings and the biochemical phenotype of a 3‐year‐old girl with ReNU syndrome. Circulating biomarkers and a muscle biopsy s uggested mild mitochondrial abnormalities. Severe plasmalogen deficiency was also observed, comparable to defects of peroxisomal plasmalogen biosynthesis.
Irene De Biase +4 more
wiley +1 more source
Effect of bile salts on intestinal epithelial function in gilthead seabream (Sparus aurata). [PDF]
Fuentes J +5 more
europepmc +1 more source

