Results 191 to 200 of about 87,175 (303)

ChREBP drives β‐cell proliferation under metabolic stress but not in pregnancy‐induced β‐cell expansion

open access: yesJournal of Diabetes Investigation, EarlyView.
ChREBP is a context‐dependent regulator of adaptive β‐cell proliferation. It plays a pivotal role in driving β‐cell expansion under pathophysiological metabolic stress, such as insulin resistance and hyperglycemia, but has a limited role during physiological expansion in pregnancy.
Sodai Kubota   +20 more
wiley   +1 more source

COX-2 strengthens the effects of acid and bile salts on human esophageal cells and Barrett esophageal cells. [PDF]

open access: yesBMC Mol Cell Biol, 2022
Jiangang S   +6 more
europepmc   +1 more source

Incidence of P200 pemphigoid: A nationwide study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen   +7 more
wiley   +1 more source

BILE SALT METABOLISM

open access: yesJournal of Biological Chemistry, 1928
H.P. Smith, A.H. Groth, G.H. Whipple
openaire   +2 more sources

Hydrophobic Bile Salts Induce Pro-Fibrogenic Proliferation of Hepatic Stellate Cells through PI3K p110 Alpha Signaling. [PDF]

open access: yesCells, 2022
Zimny S   +8 more
europepmc   +1 more source

Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen   +4 more
wiley   +1 more source

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