Results 221 to 230 of about 45,839 (288)

Proteomic Analysis Reveals the Phenotypic Heterogeneity and Tolerance Mechanisms of Halophilic <i>Vibrio parahaemolyticus</i> Under Dual Stress of Low Salinity and Bile Salts in the Human Intestine. [PDF]

Biomolecules
Guo Y, Yang B, Zhou X, Gong Z, Wang E, Pan Y, Zhao Y, Liu H.   +7 more
europepmc   +1 more source

Role of Bile Acids and Bile Salts in Acute Pancreatitis: From the Experimental to Clinical Studies. [PDF]

Pancreas, 2021
Tran QT, Tran VH, Sendler M, Doller J, Wiese M, Bolsmann R, Wilden A, Glaubitz J, Modenbach JM, Thiel FG, de Freitas Chama LL, Weiss FU, Lerch MM, Aghdassi AA.   +13 more
europepmc   +1 more source

Metabolic Fingerprints of High‐Risk Individuals for Pancreatic Cancer: A Multibiospecimen Investigation

Analysis &Sensing, Volume 6, Issue 4, July 2026.
This study presents a multimatrix untargeted metabolomics analysis of fecal, plasma, and urine samples from individuals at high risk for pancreatic cancer development. Integrated multivariate and cofactor‐adjusted models were applied to characterize cross‐matrix metabolomic associations, incorporating pancreatic magnetic resonance imaging data, sex ...
Vladyslav Dovhalyuk, Quang‐Dong Bui, Vincent Ripoll, Wiktor Rutkowski, Miroslav Vujasinovic, J.‐Matthias Löhr, Daniel Globisch   +6 more
wiley   +1 more source

A Twisted Tale: Ileocolic Intussusception in an Adult: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Excised specimen of adult intussusception. ABSTRACT Adult intussusception is a rare but serious surgical emergency with various underlying aetiologies. A high index of clinical suspicion and early diagnosis can help guide its management. The following case report describes the presentation, diagnosis, and management of an adult ileocolic ...
Wing Yin Alan Lau, Edward Tong, Selwyn Selvendran   +2 more
wiley   +1 more source

Structural modifications and augmented affinity for bile salts in enzymatically denatured egg white. [PDF]

Food Chem X
Liu C, Wu Y, Jin G, Xu B, Mei L.
europepmc   +1 more source

Is a Clinical Trial With a Non‐Bioequivalent Batch Necessary? The Critical Role of Intrasubject Variability in Olaparib Formulation Bridging by PBPK

Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 203-213, July 2026.
Although physiologically based pharmacokinetic (PBPK) modeling is increasingly being used to support oral drug formulation bridging, the acceptance by regulatory agencies is low. One of the primary concerns is the absence of clinical pharmacokinetic (PK) data from a non‐bioequivalent (non‐BE) batch during model validation.
Jin Dong, Andrea Moir, Xavier Pepin, Elizabeth Lowe, Sandy Hopkins, Weifeng Tang, Diansong Zhou   +6 more
wiley   +1 more source

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid, Ifrah Jabeen, Muhammad Inam‐ur‐Raheem, Amin Mousavi Khaneghah, Muhammad Abid, Rana Muhammad Aadil   +5 more
wiley   +1 more source

Microbially conjugated bile salts found in human bile activate the bile salt receptors TGR5 and FXR. [PDF]

Hepatol Commun
Ay Ü, Leníček M, Haider RS, Classen A, van Eijk H, Koelfat KVK, van der Kroft G, Neumann UP, Hoffmann C, Bolm C, Olde Damink SWM, Schaap FG.   +11 more
europepmc   +1 more source

From Green Extraction to Gut Bioaccessibility: Synergistic Potential of Ginkgo biloba, Astragalus membranaceus, and Salvia miltiorrhiza Phytochemicals for Functional Food Applications

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This study optimized green extraction of a synergistic tri‐herbal blend of Ginkgo biloba, Astragalus membranaceus, and Salvia miltiorrhiza. The 1:1:2 blend showed the highest TPC synergy, with probe ultrasound giving maximal phenolic recovery. The extract, rich in rosmarinic acid, chlorogenic acid, and catechin, exhibited antioxidant, antimicrobial ...
Mohamed Ibrahim Younis, Yahia Ibrahim Sallam, Khaled Fahmy Mahmoud, Rawaa H. Tlay, M. Ali Aboudzadeh, Tarek Gamal Abedelmaksoud   +5 more
wiley   +1 more source

3′‐Sialyllactose Prevents Atherosclerosis by Attenuating Chronic Inflammation via the Gut‐Immune‐Cardiovascular Axis in LDLR−/− Mice

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
3′‐SL intervention in HCD‐fed LDLR−/− mice reduces atherosclerosis, improves metabolic parameters, and suppresses inflammation. Multi‐omics integration shows that 3′‐SL remodels gut microbiota (↓ Firmicutes/Bacteroidota, ↑ Akkermansia), alters colonic metabolites and gene expression (Kng1, Ccl2, Il2ra, C6), and coordinates the gut‐immune‐cardiovascular
Yingying Zhuang, Wei Zhang, Linlin Zhou, Hui Shu, Wenqing Bo, Yiding Wang, Xinyuan Huang, Xinning Zhao, Hanying Zheng, Dongbei Guo, Xiaoxuan Chen, Lili Pan, Hongwei Li, Xinyue Wang   +13 more
wiley   +1 more source