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Ontogenetic Sequence of Differential Gene Expression in Predator‐Induced Daphnia pulex

open access: yesMolecular Ecology, Volume 35, Issue 13, July 2026.
ABSTRACT In response to predators, many Daphnia species develop inducible morphological defenses. These traits are phenotypically plastic, meaning their production is suppressed in the absence of the predator. While previous studies have identified several neurohumoral factors and candidate genes involved in the development of the defenses, the ...
Andrey Rozenberg   +5 more
wiley   +1 more source

Bile salts and cholestasis

open access: yesDigestive and Liver Disease, 2010
Bile salts have a crucial role in hepatobiliary and intestinal homeostasis and digestion. Primary bile salts are synthesized by the liver from cholesterol, and may be modified by the intestinal flora to form secondary and tertiary bile salts. Bile salts are efficiently reabsorbed from the intestinal lumen to undergo enterohepatic circulation.
Maillette de Buy Wenniger, Lucas   +1 more
openaire   +4 more sources
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Bile Salt Metabolism:I. The Physiology of Bile Salts

Australian and New Zealand Journal of Medicine, 1977
Bile salts are synthesized in the liver from cholesterol, conjugated with glycine or taurine and secreted in bile with cholesterol and lecithin. The molar concentrations of these three lipids determine solubility of cholesterol in bile. Within the gastrointestinal lumen bile salts play an essential role in lipid absorption and faty transport.
A E, Cowen, C B, Campbell
openaire   +2 more sources

Bile Salt Metabolism:II. Bile Salts and Disease

Australian and New Zealand Journal of Medicine, 1977
Alterations of bile salt metabolism have been shown in numerous diseases. Liver damage results in elevated serum bile salt concentrations which may be useful as a sensitive index of hepatocellular disease. Changes in the relative proportions of the individual bile salts in serum occur with cholestasis.
C B, Campbell, A E, Cowen
openaire   +2 more sources

Bile Salt Transporters

Annual Review of Physiology, 2002
▪ Abstract  Bile salts are the major organic solutes in bile and undergo extensive enterohepatic circulation. Hepatocellular bile salt uptake is mediated predominantly by the Na+-taurocholate cotransport proteins Ntcp (rodents) and NTCP (humans) and by the Na+-independent organic anion-transporting polypeptides Oatp1, Oatp2, and Oatp4 (rodents) and ...
Meier, Peter J., Stieger, B.
openaire   +2 more sources

Bile Salt Roles in Bile-Salt-Stimulated Lipase Activity

Journal of Pediatric Gastroenterology and Nutrition, 1986
SummaryThe hydrolysis of 4‐nitrophenylacetate and phenylsalicylate, catalyzed by human milk lipase in the presence of a range of concentrations of sodium cholate, has been measured at pH 7.3 and 37.5°C, and maximum activity was observed for both substrates at 1 mmole/ dm−3 bile salt.
C J, O'Connor, P, Walde, R G, Wallace
openaire   +2 more sources

Bile salt diarrhea

Current Gastroenterology Reports, 2005
Alterations in bile acid metabolism and in the enterohepatic circulation are often associated with chronic diarrhea and should be considered when more common causes of chronic diarrhea have been excluded. Bile acid diarrhea most often occurs in disease or resection of the terminal ileum, in which there is increased exposure of the colonic mucosa to ...
Bruce W, Robb, Jeffrey B, Matthews
openaire   +2 more sources

Solubility of Bile Salts

Nature, 1969
BILE salts are detergent-like molecules which occur widely in living systems. The dihydroxy and trihydroxy bile salts have an extraordinary ability to solubilize insoluble lipids such as phospholipids1–5, monoglycerides6 and long chain alkyl alcohols7.
D M, Small, W, Admirand
openaire   +2 more sources

Bile Salts

2013
Bile salts play a crucial role in hepatobiliary and intestinal homeostasis and digestion. The liver synthesizes primary bile salts from cholesterol. Enzymatic modifications during their enterohepatic circulation lead to the formation of secondary and tertiary bile salts.
Maillette de Buy Wenniger, Lucas   +2 more
openaire   +1 more source

Bile salts and their importance for drug absorption

open access: yesInternational Journal of Pharmaceutics, 2013
Bile salts are present in the intestines of humans as well as the animals used during the development of pharmaceutical products. This review provides a short introduction into the physical chemical properties of bile salts, a description of the bile ...
René Holm   +2 more
exaly   +2 more sources

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