Results 241 to 250 of about 87,175 (303)
The Journal of Clinical Pharmacology, Volume 66, Issue 5, May 2026.Abstract Bemnifosbuvir is a novel oral guanosine nucleotide prodrug with potent pan‐genotypic inhibitory activity against hepatitis C virus. In vitro studies assessing the inhibition or induction potential of bemnifosbuvir on the CYP450 and UGT1A1 enzymes demonstrated that bemnifosbuvir is a weak inducer and a reversible and time‐dependent inhibitor of
Xiao‐Jian Zhou +10 more
wiley +1 more source
Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue [PDF]
, 2016 et al,, Meganathan, Kesavan
core +1 more source
Journal of the Science of Food and Agriculture, Volume 106, Issue 7, Page 4008-4016, May 2026.Abstract BACKGROUND This study assessed the effects of dietary carnosine during the in vitro digestion of a healthy meal model based on the Mediterranean diet, comprising lean pork enriched with two levels of carnosine, whole grain bread, tomato, onion, and olive oil.
Yi Yao Li +6 more
wiley +1 more source
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.Moderate inclusion (20–30%) of cassava starch residue in broiler diets improved gut morphology and reduced E. coli counts with minimal adverse effects, while higher levels impaired growth and liver health. The findings highlight CSR's potential as a partial maize replacement, but caution is needed at elevated inclusion rates.
Agnes Osei‐Adjei +8 more
wiley +1 more source
How Salmonella Works Under Osmotic and Desiccation Stresses
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT Salmonella remains one of the leading threats in foods with reduced water activity, where it can survive for long periods and cause outbreaks. Its persistence stems from a wide array of adaptive strategies shaped by the selective pressures imposed by low‐moisture foods.
Mayara Messias Oliveira +2 more
wiley +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT This review addresses the processing aspects and integrates in vitro and in vivo findings to highlight the various health benefits of indigenous fermented fish products from different regions of the world. Across Asia, Africa, and Northern Europe, fermented fish holds cultural significance, with each region boasting unique varieties shaped by ...
Banlambhabok Khongthaw +6 more
wiley +1 more source
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT In the context of the circular economy and the increasing demand for safe and sustainable packaging, this work addresses the safety assessment of food contact materials (FCMs) derived from agro‐industrial by‐products. Despite growing interest in these bio‐based materials, the literature still lacks a structured safety‐assessment framework able
Marianna Ciccone +6 more
wiley +1 more source
Safety of Immune Checkpoint Inhibitors Prior to Liver Transplantation in Hepatocellular Carcinoma
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 10, Page 1369-1379, May 2026.Patients who received immune checkpoint inhibitors before liver transplant for the treatment of hepatocellular carcinoma had rejection and survival outcomes comparable to those without ICI exposure. Most rejection episodes were effectively managed with medical therapy.
L. Aceituno +21 more
wiley +1 more source
Review Article: Targeting Peroxisome Proliferator‐Activated Receptors in Primary Biliary Cholangitis
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 9, Page 1215-1235, May 2026.Peroxisome proliferator‐activated receptor (PPAR) agonists have emerged as important second‐line treatments in primary biliary cholangitis, with profiles influenced by different selectivity for α‐, δ‐ and γ‐isoforms. PPAR‐α and PPAR‐δ agonism improve cholestasis, with inflammation reduced via all isoforms. PPAR‐δ agonism also reduces pruritus.
Jörn M. Schattenberg +8 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 9, Page 1747-1778, May 2026.Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska +2 more
wiley +1 more source