Results 111 to 120 of about 282,772 (364)

Some blood biochemical indices of mice with pttg gene knockout

Біологічні студії, 2011
Liver injury of any etiology is accompanied by increased fibrogenesis. One of the key genes that may influence in the development of liver fibrosis, is pttg gene (Pituitary tumor transforming gene).
O. P. Kanyuka, Ye. Z. Filyak, S. V. Afanasyev, N. O. Sybirna   +3 more
doaj   +1 more source

The physiology of bilirubin: health and disease equilibrium.

Trends in Molecular Medicine, 2023
L. Vítek, T. Hinds, D. Stec, C. Tiribelli   +3 more
semanticscholar   +1 more source

Bilirubin Is Inversely Associated With Cardiovascular Disease Among HIV‐Positive and HIV‐Negative Individuals in VACS (Veterans Aging Cohort Study)

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Bilirubin may protect against cardiovascular disease (CVD) by reducing oxidative stress. Whether elevated bilirubin reduces the risk of CVD events among HIV + individuals and if this differs from uninfected individuals remain unclear.
V. Marconi, Meredith S. Duncan, K. So-Armah, V. Re, Joseph K. Lim, A. Butt, M. Goetz, M. Rodriguez‐Barradas, C. Alcorn, J. Lennox, J. Beckman, A. Justice, M. Freiberg   +12 more
semanticscholar   +1 more source

On continuous distribution functions, minimax and best invariant estimators, and integrated balanced loss functions [PDF]

arXiv, 2013
We consider the problem of estimating a continuous distribution function $F$, as well as meaningful functions $\tau(F)$ under a large class of loss functions. We obtain best invariant estimators and establish their minimaxity for H\"{o}lder continuous $\tau$'s and strict bowl-shaped losses with a bounded derivative.
arxiv  

Bilirubin Conjugation and Biliary Bilirubin Excretion after Intravenous Bilirubin Injection in Dogs.

The Tohoku Journal of Experimental Medicine, 1991
This study was undertaken to investigate the bilirubin clearance, bilirubin conjugation and biliary bilirubin excretion after an intravenous single bilirubin injection (5 mg/kg or 10 mg/kg) in 10 mongrel dogs. Serum total bilirubin concentration increased after the bilirubin injection, and then it immediately decreased.
Haruyuki Inoue, Shoichi Satoh, Hideo Ise, Ritsuo Usui, Yutaka Abe, Seiki Matsuno, Akihito Moriyasu, Yoshiyuki Hirama, Hirohito Hayasaka, Osamu Kitayama, Noriyoshi Suzuki, Hiroshi Honda   +11 more
openaire   +4 more sources

Bilirubin Binding to PPARα Inhibits Lipid Accumulation

PLoS ONE, 2016
Numerous clinical and population studies have demonstrated that increased serum bilirubin levels protect against cardiovascular and metabolic diseases such as obesity and diabetes. Bilirubin is a potent antioxidant, and the beneficial actions of moderate
D. Stec, K. John, Christopher J Trabbic, Amarjit Luniwal, Michael W. Hankins, J. Baum, T. Hinds   +6 more
semanticscholar   +1 more source

Association between surgical difficulty and tumor location based on subsegments of the Glisson branches in laparoscopic liver resection

Annals of Gastroenterological Surgery, EarlyView.
Our study validates the need for a more detailed and accurate tumor location scoring system within the IWATE criteria. The proposed classification based on subsegmental Glisson branches provides a sophisticated tool for assessing LLR difficulty. By providing a more detailed assessment, this new system has the potential to enhance surgical planning ...
Taisuke Imamura, Yusuke Yamamoto, Ryo Morimura, Hisashi Ikoma, Tomohiro Arita, Hirotaka Konishi, Atsushi Shiozaki, Takeshi Kubota, Hitoshi Fujiwara, Eigo Otsuji   +9 more
wiley   +1 more source

Evaluation of ABCA1 gene polymorphism as a prognostic index of fibrosis progression in NAFLD patients

Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
Dyslipidemias, hepatic steatosis index, and ABCA1 (rs1800977) gene polymorphism CC genotype; were the only independent predictors of advanced fibrosis in NAFLD‐patients. Abstract Introduction It had been evident that non‐alcoholic fatty liver disease (NAFLD) is the new era epidemic.
Samar E. Ghanem, Maha M. Elsabaawy, Mervat M. Abdelkareem, Marwa L. Helal, Warda Othman, Mahitab Elsayed, Dalia M. Elsabaawy, Ashraf El Fert   +7 more
wiley   +1 more source

Impact of gastrectomy on efficacy and safety of second‐line chemotherapy patients with advanced gastric cancer: Exploratory analysis of two randomized phase III trials

Annals of Gastroenterological Surgery, EarlyView.
In an analysis of two RCTs of IRI‐based second‐line chemotherapy for AGC, patients with prior gastrectomy had better OS and PFS than patients without prior gastrectomy. Furthermore, patients with prior gastrectomy had a better prognosis in OS and PFS adjusted for background factors as well. Abstract Aims Second‐line chemotherapy (SLC) improves survival
Kazuhiro Nishikawa, Wasaburo Koizumi, Akira Tsuburaya, Motoko Suzuki, Satoshi Morita, Kazumasa Fujitani, Yusuke Akamaru, Ken Shimada, Hisashi Hosaka, Ken Nishimura, Takaki Yoshikawa, Toshimasa Tsujinaka, Junichi Sakamoto   +12 more
wiley   +1 more source

Measurement of direct bilirubin by use of bilirubin oxidase.

Clinical Chemistry, 1987
Abstract We developed an enzymatic method for measuring direct-reacting bilirubin (DBIL) in serum. At pH 4.5, bilirubin oxidase (BOX) oxidizes mono-conjugated bilirubin, di-conjugated bilirubin, and most of the delta-bilirubin to biliverdin.
L Davis, Billy W. Perry, Basil T. Doumas, B Jendrzejczak   +3 more
openaire   +3 more sources