Results 111 to 120 of about 109,357 (257)

Identification of Prognostic Factors and Regulatory Pathways in Porto‐Sinusoidal Vascular Disorder

open access: yesLiver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background and Aims Porto‐sinusoidal vascular disorder (PSVD) is a rare liver condition characterized by specific histological features primarily affecting the hepatic sinusoidal and periportal vasculature, in the absence of cirrhosis. This study aimed to identify prognostic factors and regulatory pathways associated with PSVD by integrating ...
Subin Heo   +19 more
wiley   +1 more source

An Unusual Case of Rapidly Progressive Hyperbilirubinemia

open access: yesCase Reports in Pediatrics, 2013
We present an unusual case of hyperbilirubinemia with rapid early progression leading to bilirubin encephalopathy in a term neonate. Despite early recognition and intervention, the total serum bilirubin reached a maximum level of 39 mg/dL at 32 hours of ...
Kimberly M. Thornton   +7 more
doaj   +1 more source

Neonatal hyperbilirubinemia bilirubin encephalopathy: investigations into the diagnosis, epidemiology, pathogenesis, management and treatment of the jaundiced newborn [PDF]

open access: yes, 2009
Jaundice is probably the most common newborn infant problem dealt with on a daily basis by the family practitioner and paediatrician. Jaundice occurs when the liver cannot clear a sufficient amount of bilirubin from the plasma.
Maisels, Michael Jeffrey
core  

Glymphatic System Dysfunction and its Associated Factors in Wilson's Disease: A DTI–ALPS Study

open access: yesBrain and Behavior, Volume 16, Issue 10, October 2026.
Glymphatic function, assessed by DTI‐ALPS index, was impaired in neurological Wilson's disease compared with hepatic phenotype and controls. Age, AST, and UWDRS‐I score independently predicted dysfunction, linking neurodegeneration, liver injury, and altered glymphatic activity. ABSTRACT Background Wilson's disease (WD) is a genetic disorder of copper (
Ling Zhu   +14 more
wiley   +1 more source

Integrated machine learning identifies biomarkers for bilirubin-induced Alzheimer’s disease-like lesions in neonates and adults

open access: yesScientific Reports
Neurological impairments resulting from bilirubin encephalopathy represent a hallmark of bilirubin’s neurotoxic effects. Earlier research suggests that bilirubin may contribute to Alzheimer’s disease (AD) pathology by inducing neuronal necrosis and ...
Wenhao Bao   +6 more
doaj   +1 more source

Bilirubin-microbiota interaction: molecular mechanisms and therapeutic strategies in neonatal jaundice

open access: yesFrontiers in Microbiology
Recent studies have revealed a complex interplay between bilirubin metabolism and the gut microbiota. Bilirubin functions as a potent antioxidant and signaling molecule in humans, and its concentration-dependent effects on distinct microbial taxa ...
Wenlong Yan   +6 more
doaj   +1 more source

Scrub Typhus Meningoencephalitis With Concurrent Brucellosis in Rural Nepal: Diagnostic Challenges With Negative PCR in a Low‐Resource Setting

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
Scrub typhus meningoencephalitis with concurrent Brucellosis. ABSTRACT Scrub typhus is an important cause of acute febrile illness in Nepal and can rarely present with meningoencephalitis and multiorgan involvement. We report a 32‐year‐old female farmer from rural Nepal who presented during the monsoon season with high‐grade fever, myalgia, vomiting ...
Pashupati Pokharel   +6 more
wiley   +1 more source

Yellow cerebrospinal fluid in an extremely preterm infant: a case report

open access: yesFrontiers in Cellular Neuroscience
Although phototherapy has reduced the incidence of kernicterus in term infants, it remains a significant threat to extremely preterm infants due to their immature blood–brain barrier and frequent comorbidities such as sepsis.
Xiyang Chen   +8 more
doaj   +1 more source

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