Results 191 to 200 of about 20,671 (222)
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Rinsho byori. The Japanese journal of clinical pathology, 1992
Fructosamine is examined as the index of past mean blood glucose levels. However, the fructosamine value appears to be influenced by the bilirubin. Therefore, we examined patients with hyperbilirubinemia showing suspected and definite jaundice. Abnormal fructosamine values were noted in 9 out of the 50 cases (18%) with suspected jaundice and 40 out of ...
Y, Ohisa +3 more
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Fructosamine is examined as the index of past mean blood glucose levels. However, the fructosamine value appears to be influenced by the bilirubin. Therefore, we examined patients with hyperbilirubinemia showing suspected and definite jaundice. Abnormal fructosamine values were noted in 9 out of the 50 cases (18%) with suspected jaundice and 40 out of ...
Y, Ohisa +3 more
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Oral Treatment for Jaundice Using Immobilized Bilirubin Oxidase
Artificial Organs, 1992Abstract: Jaundice is characterized by an excessive accumulation of bilirubin in the blood and tissues. A novel approach to reduce plasma levels of bilirubin by blocking its enterohepatic circulation was investigated. The treatment consisted of oral administration of immobilized bilirubin oxidase, which could oxidize bilirubin in the intestine to less
P J, Soltys, C, Mullon, R, Langer
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Authentic and Recombinant Bilirubin Oxidases Are in Different Resting Forms
Bioscience, Biotechnology, and Biochemistry, 2003Myrothecium verrucaria bilirubin oxidase expressed in Aspergillus oryzae is in a resting form different from that of the authentic bilirubin oxidase, but reaches the resting form of the authentic enzyme after one cycle of reduction and reoxidation with dioxygen as shown by the absorption and electron paramagnetic resonance spectra.
Takeshi, Sakurai +6 more
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Quantification of plasma hemoglobin in the presence of bilirubin with bilirubin oxidase.
Annals of clinical and laboratory science, 1995Owing to the overlapping absorption bands of hemoglobin and bilirubin, spectrophotometric determination of plasma free hemoglobin has been plagued by the interference of bilirubin when the latter is present in significant concentrations. To resolve this problem, bilirubin oxidase from Myrothecium verrucaria has been used to remove bilirubin in icteric ...
S S, Wong, O J, Schenkel
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On the stability of the “wired” bilirubin oxidase oxygen cathode in serum
Bioelectrochemistry, 2006Oxygen is electroreduced to water on the "wired" bilirubin oxidase (w-BOD) catalyst at a considerably lesser potential than on pure platinum. The w-BOD catalyst could be of value in an implantable glucose-O2 biofuel cell, operating living tissue, if it were stable in serum. We found, however, that w-BOD loses its activity in a few hours in the combined
Chan, Kang, Hyosul, Shin, Adam, Heller
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Characterization of Copper Atoms in Bilirubin Oxidase by Spectroscopic Analyses
The Journal of Biochemistry, 1989Bilirubin oxidase [EC 1.3.3.5], purified from the culture medium of Myrothecium verrucaria, was found to contain two blue copper atoms per protein molecule with a molecular weight of ca. 52 kDa. The two copper atoms were estimated to be in the all cupric state by the cuproine colorimetric method and also atomic absorption analysis.
Y, Gotoh +4 more
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Deactivation of bilirubin oxidase by a product of the reaction of urate and O2
Bioelectrochemistry, 2004The "wired" bilirubin oxidase (BOD) bioelectrocatalyst is superior to pure platinum as an electrocatalyst of the four-electron electroreduction of O(2) to water. Not only is its overpotential for O(2) reduction lower, but unlike platinum, it is not affected by organic compounds like glucose. The "wired" BOD-coated carbon cathode operates for >1 week at
Chan, Kang +3 more
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Bilirubin oxidase bioelectrocatalytic cathodes: the impact of hydrogen peroxide
Chem. Commun., 2014Mediator-less, direct electro-catalytic reduction of oxygen to water by bilirubin oxidase (Myrothecium sp.) was obtained on anthracene-modified, multi-walled carbon nanotubes. H2O2 was found to significantly and irreversibly affect the electro-catalytic activity of bilirubin oxidase, whereas similar electrodes comprised of laccase (Trametes versicolor)
Milton, R +4 more
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Design of a thermostable bilirubin oxidase from Myrothecium verrucaria
Journal of Bioscience and BioengineeringBilirubin oxidase (BOD), identified as a multicopper oxidase produced by Myrothecium verrucaria, plays a critical role in the oxidation of bilirubin to biliverdin, which is pivotal in various biochemical processes. To construct a highly thermostable BOD, we have used three protein engineering methods: (i) stabilization of the main chain (proline ...
Haruka Kado Horiguchi +10 more
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Mechanistic Study of Direct Electron Transfer in Bilirubin Oxidase
ECS Meeting Abstracts, 2012Abstract not Available.
Shayna Brocato +2 more
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