Results 11 to 20 of about 107,951 (150)
Go Green: The Antiinflammatory Effects of Biliverdin Reductase [PDF]
Frontiers in Pharmacology, 2012 Biliverdin (BV) has emerged as a cytoprotective and important anti-inflammatory molecule. Conversion of BV to bilirubin (BR) is catalyzed by biliverdin reductase (BVR) and is required for the downstream signaling and nuclear localization of BVR.
Barbara eWegiel, Leo eOtterbein
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Biliverdin Reductase: a Target for Cancer Therapy? [PDF]
Frontiers in Pharmacology, 2015 Biliverdin reductase (BVR) is a multifunctional protein that is the primary source of the potent antioxidant, bilirubin. BVR regulates activities/functions in the insulin/IGF-1/IRK/PI3K/MAPK pathways.
Peter eGibbs +2 more
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Biliverdin Reductase-A Deficiency Brighten and Sensitize Biliverdin-binding Chromoproteins [PDF]
Cell Structure and Function, 2020 Tissue absorbance, light scattering, and autofluorescence are significantly lower in the near-infrared (NIR) range than in the visible range. Because of these advantages, NIR fluorescent proteins (FPs) are in high demand for in vivo imaging. Nevertheless, application of NIR FPs such as iRFP is still limited due to their dimness in mammalian cells.
Sumiyama, Kenta +5 more
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The specificity of biliverdin reductase
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1984 The specificity of rat liver biliverdin reductase was examined with the help of a series of synthethic biliverdins. The mixture of the four biliverdin isomers obtained by the chemical oxidation of protohemin I, protohemin XI, protohemin XIV and ...
Josefina Awruch +3 more
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Combined fluorometric analysis of biliverdin and bilirubin by the recombinant protein HUG [PDF]
MethodsXBiliverdin is a secondary metabolite of heme catabolism. It is formed by the reaction catalyzed by heme oxygenase, which converts the heme group contained in proteins such as hemoglobin, myoglobin, cytochromes, and catalase into biliverdin, iron (II) and
Federica Tramer +5 more
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Biliverdin reductase and bilirubin in hepatic disease [PDF]
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2018 The buildup of fat in the liver (hepatic steatosis) is the first step in a series of incidents that may drive hepatic disease. Obesity is the leading cause of nonalcoholic fatty liver disease (NAFLD), in which hepatic steatosis progresses to liver disease.
Lauren Weaver +3 more
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The Heme Oxygenase/Biliverdin Reductase System as Effector of the Neuroprotective Outcomes of Herb-Based Nutritional Supplements [PDF]
Frontiers in Pharmacology, 2019 Over the last few years, several preclinical studies have shown that some herbal products, such as ferulic acid, Ginkgo biloba, and resveratrol, exert neuroprotective effects through the modulation of the heme oxygenase/biliverdin reductase system ...
Emanuela Mhillaj +4 more
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Biomolecules, 2020 Biliverdin reductase (BVR) is an enzymatic and signaling protein that has multifaceted roles in physiological systems. Despite the wealth of knowledge about BVR, no data exist regarding its actions in adipocytes.
David E. Stec +6 more
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Nature CommunicationsPerformance of near-infrared probes and optogenetic tools derived from bacterial phytochromes is limited by availability of their biliverdin chromophore.
Ludmila A. Kasatkina +12 more
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Biliverdin reductase: more than a namesakeThe reductase, its peptide fragments and biliverdin regulate activity of the three classes of protein kinase C. [PDF]
Frontiers in Pharmacology, 2012 The expanse of human biliverdin reductase (hBVR) functions in the cells is arguably umatched by any single protein. hBVR is a Ser/Thr/Tyr kinase, a scaffold protein, a transcription factor and an intracellular transporter of gene regulators.
Peter E.M. Gibbs +2 more
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