Results 21 to 30 of about 1,516 (196)

Fingerprint Analysis of Buriti (Mauritia flexuosa) Using Paper Spray Mass Spectrometry [PDF]

Journal of Mass Spectrometry, Volume 60, Issue 8, August 2025.
ABSTRACT A straightforward and efficient approach using paper spray ionization mass spectrometry (PS‐MS) was employed to detect fixed constituents in all anatomical parts of buriti, a native Brazilian fruit. This ambient mass spectrometry technique requires minimal sample preparation and was applied in both positive and negative ion modes. In total, 61
Bruna V. Nunes, Ana Luiza C. C. Ramos, Talvane Coelho, Viviane D. M. Silva, Afonso Henrique de Oliveira Júnior, Ricardo Manuel de Seixas Boavida Ferreira, Rodinei Augusti, Raquel L. B. de Araújo, Julio Onesio‐Ferreira Melo   +8 more
wiley   +2 more sources

Inhibitors of Sodium‐Dependent Serotonin Transporter Protein (SERT) as Potential New Nematicides [PDF]

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
ABSTRACT Nematodes of the genus Meloidogyne cause major losses in agricultural production worldwide. To identify potentially useful chemical structures for developing new nematicides, this study initially aimed to determine in silico – using computationally efficient techniques – the protein target of chaetoglobosins A and B in these nematodes.
Geraldo Jamisse Hodela, Vitor Pereira de Sousa, Mariana Castro de Melo, Rodrigo Martins Fráguas, Willian César Terra, Denilson Ferreira de Oliveira   +5 more
wiley   +2 more sources

Phytochemicals with potential NMDAR-inhibitory activities: a review of neuroprotective mechanisms against excitotoxicity [PDF]

Saudi Pharmaceutical Journal
The N-methyl-D-aspartate receptors (NMDARs) are ionotropic glutamate receptors in the central nervous system (CNS) that play a crucial role in synaptic plasticity, learning, and memory. However, NMDAR overstimulation is a critical pathological feature in
Abdulmohsin J. Alamoudi
doaj   +2 more sources

RETRACTED ARTICLE: Bilobalide protects H9c2 cell from oxygen-glucose-deprivation-caused damage via upregulation of miR-27a

Artificial Cells, Nanomedicine, and Biotechnology, 2019
We, the Editors and Publisher of the journal Artificial Cells, Nanomedicine, and Biotechnology, have retracted the following article:Ailin Cao and Xiangting Li. (2019).
Ailin Cao, Xiangting Li
doaj   +2 more sources

Self-assembled low molecular weight chitosan-bilobalide microsuspension protects hippocampal toxicity in amyloid beta(25–35) induced mice

Carbohydrate Polymer Technologies and Applications
Alzheimer's disease (AD) is a progressive neurological disorder and is characterized by the accumulation of amyloid beta (Aβ) peptide and hyperphosphorylated tau as a pathological hallmark.
P. Pramod Kumar, K.V. Harish Prashanth
doaj   +2 more sources

The potential value of traditional Chinese medicine monomers in cerebral ischemia–reperfusion injury: a network meta-analysis based on animal model [PDF]

BMC Complementary Medicine and Therapies
Background Cerebral ischemia–reperfusion injury (CIRI) is a complex pathological process, which can further aggravate the damage of ischemic tissues. Traditional Chinese medicine (TCM) monomers, bioactive compounds extracted from Chinese herbal medicines,
Xin Luo, Jing-Yuan Niu, Hui-Sheng Chen
doaj   +2 more sources

Metabolomic and chemometric profiling of crimson grapes during drying and its impact on antidiabetic activity [PDF]

npj Science of Food
The present study investigates the metabolic profile and antidiabetic potential of Crimson Seedless grapes during the drying process using UPLC–QTOF-MS/MS and multivariate statistical analyses.
Doaa M. Abo-Atya, Doaa A. Ghareeb, Badr Aldahmash, Shaden A. M. Khalifa, Hesham R. El-Seedi, Eman Shawky, Dina S. Ghallab   +6 more
doaj   +2 more sources

Synthesis and Mechanistic Interrogation of Ginkgo biloba Chemical Space en route to (–)-Bilobalide [PDF]

, 2020
Here we interrogate the structurally dense (1.63 mcbits/Å3) GABAA receptor antagonist bilobalide, intermediates en route to its synthesis and related mechanistic questions.
Stefano Forli (6949025), Masaki Ohtawa (6752454), Robert Demoret (8714862), Kendall N Houk (8014379), Ryan Shenvi (4370713), Meghan Baker (6752357), Ching-Ching Lam (8714883), Shuming Chen (8097701)   +7 more
core   +3 more sources

Role of GABAergic antagonism in the neuroprotective effects of bilobalide [PDF]

Brain Research, 2007
Bilobalide, a constituent of Ginkgo biloba, has neuroprotective properties. Its mechanism of action is unknown but it was recently found to block GABA(A) receptors. The goal of this study was to test the potential role of a GABAergic mechanism for the neuroprotective activity of bilobalide.
Cornelia, Kiewert, Vikas, Kumar, Oksana, Hildmann, Misty, Rueda, Joachim, Hartmann, Runa S, Naik, Jochen, Klein   +6 more
openaire   +2 more sources

Bilobalide Alleviated Dextran Sulfate Sodium-Induced Experimental Colitis by Inhibiting M1 Macrophage Polarization Through the NF-κB Signaling Pathway

Frontiers in Pharmacology, 2020
Bilobalide, a unique Ginkgo biloba constituent has attracted significant interest as a novel therapeutic option for neuronal protection. However, there is paucity of data on its effect on colitis.
Heng Zhang, Nengqi Cao, Zhilong Yang, Xingchao Fang, Xinyu Yang, Hao Li, Zhi Hong, Zhenling Ji   +7 more
doaj   +1 more source