Results 31 to 40 of about 2,617,421 (301)

Establishment of competitive binding assay to detect and differentiate hepatitis E virus infection

open access: yesAnnals of Hepatology, 2019
Introduction and Objectives: This study was undertaken to demonstrate a promising approach for detection and differentiation the serum immunoglobulin G (IgG) against hepatitis E virus (anti-HEV IgG) using a competitive binding assay established with ...
Jiyue Wen, Weizhuo Lu, Jihong Meng
doaj   +1 more source

Thermodynamics of competitive molecular channel transport: application to artificial nuclear pores. [PDF]

open access: yesPLoS ONE, 2010
In an analytical model channel transport is analyzed as a function of key parameters, determining efficiency and selectivity of particle transport in a competitive molecular environment.
Wolfgang R Bauer, Walter Nadler
doaj   +1 more source

Competitive CarboxylateSilicate Binding at Iron Oxyhydroxide Surfaces

open access: yes, 2021
Dissolved silicate ions in wet and dry soils can determine the fate of organic contaminants via competitive binding. While fundamental surface science studies have advanced knowledge of binding in competitive systems, little is still known about the ...
Khalil Hanna   +7 more
core   +1 more source

Characterisation of the Binding Properties of Bacillus Thuringiensis 18 Toxin on Leukaemic Cells

open access: yesJournal of Experimental & Clinical Cancer Research, 2010
Background Various strains of Bacillus thuringiensis (Bt) have been found to produce parasporal proteins that are cytotoxic to human cancer cells. This study aims to establish the binding affinity of purified Bt 18 toxin for CEM-SS (T lymphoblastic ...
Nadarajah Vishna D   +3 more
doaj   +1 more source

Effects of combined binding of chlorogenic acid/caffeic acid and gallic acid to trypsin on their synergistic antioxidant activity, enzyme activity and stability

open access: yesFood Chemistry: X, 2023
The combined application of multiple natural polyphenols in functional foods may provide better health benefits. The binding of polyphenols with different structures to proteins will affect their respective functions.
Xin Qi   +9 more
doaj   +1 more source

6-Arylpyrido[2,3-d]pyrimidines as novel ATP-competitive inhibitors of bacterial D-alanine:D-alanine ligase. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: ATP-dependent D-alanine:D-alanine ligase (Ddl) is a part of biochemical machinery involved in peptidoglycan biosynthesis, as it catalyzes the formation of the terminal D-ala-D-ala dipeptide of the peptidoglycan precursor UDPMurNAc ...
Veronika Škedelj   +13 more
doaj   +1 more source

Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles: comprehensive spectroscopic study

open access: yesBMC Chemistry, 2023
The direct binding of antiviral agents; Daclatasvir and valacyclovir and green synthesized nanoparticles to salmon sperm DNA have been assessed in a comparative study.
Ahmed Faried Abdel Hakiem   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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