Results 31 to 40 of about 2,748,278 (304)

Competitive Binding of Parkinsonian‐inducing Neurotoxins to Neuromelanin [PDF]

, 2016
Competitive Binding of Parkinsonian‐inducing Neurotoxins to NeuromelaninHaining, Robert (faculty ...
Hernandez, Aubrey
core   +2 more sources

Analysis of a Mathematical Model of Real-Time Competitive Binding on a Microarray [PDF]

, 2022
A mathematical model of competitive binding on a microarray in real-time yields a planar system of nonlinear ordinary differential equations. This model can be used to explore dimensionless formulation, linear approximation, and reduction.
Lynch, Frank H, Frank Lynch
core   +1 more source

Cooperation, Competition, and Ties That Bind

The Canadian Journal of Hospital Pharmacy, 2019
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openaire   +3 more sources

High glucose disrupts oligosaccharide recognition function via competitive inhibition : a potential mechanism for immune dysregulation in diabetes mellitus [PDF]

, 2011
Diabetic complications include infection and cardiovascular disease. Within the immune system, host-pathogen and regulatory host-host interactions operate through binding of oligosaccharides by C-type lectin.
Bee K. Tan, Robert B. Sim, Russell Wallis, Tan, Bee K., Elizabeth J. Soilleux, Townsend, Paul, Wallis, Russell, Soilleux, Elizabeth J., Paul Townsend, Daniel A. Mitchell, Randeva, Harpal S., Sim, Robert B., Hendrik Lehnert, Ilyas, Rebecca, Zehnder, Daniel, Mitchell, Daniel A., Daniel Zehnder, Rebecca Ilyas, Harpal S. Randeva, Lehnert, Hendrik   +19 more
core   +1 more source

Competitive binding curves of characteristic ligands to recombinant HoblOBP4.

, 2013
The chemical structures of the ligands are shown on the right. (A) Competitive binding curves of aliphatic alcohols and aldehydes with six carbon numbers. (B) Competitive binding curves of different structural on terpenoids with ten carbon numbers.
Li Guan (115858), Bing Wang (126120), Tao Zhong (501589), Kebin Li (327882), Jiao Yin (327876), Yazhong Cao (327881)   +5 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Assessment of binding interaction to salmon sperm DNA of two antiviral agents and ecofriendly nanoparticles: comprehensive spectroscopic study

BMC Chemistry, 2023
The direct binding of antiviral agents; Daclatasvir and valacyclovir and green synthesized nanoparticles to salmon sperm DNA have been assessed in a comparative study.
Ahmed Faried Abdel Hakiem, Ahmed Mohsen Kamal El-Sagheir, Mohammed E. Draz, Niveen A. Mohamed, Ahmed Safwat Aboraia   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Unraveling competitive protein interactions: A critical step toward improved production and therapeutics

Journal of Advanced Research
Background: Competitive protein binding plays a pivotal role in regulating biological processes by influencing how proteins interact with shared ligands or binding sites.
Yuan Tian, Xiao-Yue Zhang, Mehtab Muhammad Aslam, Muhammad Yahya Tahir, Meisam Zargar, Jingjing Huang, Fu-Yuan Zhu, MoXian Chen, Li-sheng Wan, Ying-Gao Liu   +9 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source