Results 41 to 50 of about 2,748,278 (304)

Effects of combined binding of chlorogenic acid/caffeic acid and gallic acid to trypsin on their synergistic antioxidant activity, enzyme activity and stability

Food Chemistry: X, 2023
The combined application of multiple natural polyphenols in functional foods may provide better health benefits. The binding of polyphenols with different structures to proteins will affect their respective functions.
Xin Qi, He Liu, Yongfang Ren, Yihao Zhu, Qiulu Wang, Yanqing Zhang, Yushu Wu, Lixia Yuan, Hui Yan, Min Liu   +9 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Binding affinities of ligands to GmolGOBP1 and 2 evaluated via competitive binding assays by using the fluorescent probe, 1-NPN.

, 2016
Binding affinities of ligands to GmolGOBP1 and 2 evaluated via competitive binding assays by using the fluorescent probe, 1-NPN.
Guangwei Li (822910), Guohui Zhang (287129), Yiping Li (139011), Boliao Li (2735368), Xiulin Chen (2735371), Junxiang Wu (822911)   +5 more
core   +1 more source

A competitive binding between O2 and epoxy with carbon nanotubes

AIP Advances, 2017
Simulation and observation reveal a competitive binding between O2 and epoxy with carbon nanotubes. Air absorption limits tube-polymer interacting coverage and weakens the van der Waals forces.
Hsin-Jung Tsai, Yu-Ying Su, Chao-Chi Tseng, Wen-Kuang Hsu   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Interactions Between Sirolimus and Anti-Inflammatory Drugs: Competitive Binding for Human Serum Albumin [PDF]

Advanced Pharmaceutical Bulletin, 2016
Purpose: The aim of the present study was investigating the effects of three anti-inflammatory drugs, on Sirolimus protein biding. The binding site of Sirolimus on human serum albumin (HSA) was also determined.
Arash Khodaei, Soheila Bolandnazar, Hadi Valizadeh, Leila Hasani, Parvin Zakeri-Milani   +4 more
doaj   +1 more source

Binding Properties of Odorant-Binding Protein 4 of Tirathaba rufivena to Areca catechu Volatiles

Plants, 2022
Odorant-binding proteins (OBPs) play a key role in the olfactory system and are essential for mating and oviposition host selection. Tirathaba rufivena, a serious lepidopterous insect pest of the palm area in recent years, has threatened cultivations of ...
Xiang Zhou, Zheng Wang, Guangchao Cui, Zimeng Du, Yunlong Qian, Shumei Yang, Minghui Liu, Jixing Guo   +7 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Apparent dissociation constants for the binding of different sugars to MhPA14, using the competitive binding assay.

, 2019
Apparent dissociation constants for the binding of different sugars to MhPA14, using the competitive binding assay.
Peter L. Davies (121653), Shayan Assaie-Ardakany (7027148), Brigid Conroy (7027151), Shuaiqi Guo (121638), Tyler D. R. Vance (3365498)   +4 more
core   +1 more source

Identification and Functional Analysis of SlitOBP11 From Spodoptera litura

Frontiers in Physiology, 2021
Odorant binding proteins (OBPs) play a key role in the olfactory recognition of insects, whose functions have been extensively studied in adult insects but rarely in larvae.
Jiaojiao Luo, Jiaojiao Luo, Jiaojiao Luo, Zan Zhang, Zan Zhang, Zan Zhang, Dongzhen Li, Jie Liu, Jie Liu, Jie Liu, Kun Li, Kun Li, Kun Li, Xiao Sun, Lin He, Lin He, Lin He   +16 more
doaj   +1 more source