Results 11 to 20 of about 8,384,443 (422)
Genome-wide organization of eukaryotic pre-initiation complex is influenced by nonconsensus protein-DNA binding [PDF]
Biophysical Journal 104, 1107 (2013), 2013 Genome-wide binding preferences of the key components of eukaryotic pre-initiation complex (PIC) have been recently measured with high resolution in Saccharomyces cerevisiae by Rhee and Pugh (Nature (2012) 483:295-301). Yet the rules determining the PIC binding specificity remain poorly understood.
Afek, Ariel, Lukatsky, David B.
arxiv +4 more sources
Remote Sensing, 2021 Envisat’s MERIS and its successor Sentinel OLCI have proven invaluable for documenting algal bloom conditions in coastal and inland waters. Observations over turbid eutrophic waters, in particular, have benefited from the band at 708 nm, which captures ...
Chuiqing Zeng, Caren E. Binding
doaj +1 more source
Adsorption isotherm and mechanism of $\mathrm{Ca^{2+}}$ binding to polyelectrolyte [PDF]
, 2023 Polyelectrolytes, such as polyacrylic acid (PAA), can effectively mitigate $\mathrm{CaCO_3}$ scale formation. Despite their success as antiscalants, the underlying mechanism of $\mathrm{Ca^{2+}}$ binding to polyelectrolyte chains remains unresolved. Through all-atom molecular dynamics simulations, we construct an adsorption isotherm of $\mathrm{Ca^{2+}}
arxiv +1 more source
To bind, or not to bind, that is the question…
IUCrJ, 2022 The unexpected findings that are described by Czub et al. [IUCrJ (2022), 9, 551-561] provide a very interesting study demonstrating how small differences in structure can result in significant changes in the relative affinities of the seemingly promiscuous binding sites that are seen with serum albumins.
openaire +3 more sources
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
Science, 2020 Targeting the SARS-CoV-2 spike The surface of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) is decorated with trimeric spikes that bind to host cell receptors.
M. Yuan +7 more
semanticscholar +1 more source
Frontiers in Neuroanatomy, 2020 In therian mammals, the cerebellum is one of the late developing structures in the brain. Specifically, the proliferation of cerebellar granule cells occurs after birth, and even in humans, the generation of these cells continues during the first year of
Beata Tepper +6 more
doaj +1 more source
Cellular & Molecular Immunology, 2020 The outbreak of Coronavirus Disease 2019 (COVID-19) has posed a serious threat to global public health, calling for the development of safe and effective prophylactics and therapeutics against infection of its causative agent, severe acute respiratory ...
Wanbo Tai +7 more
semanticscholar +1 more source
The rna-binding ubiquitin ligase mex3a affects glioblastoma tumorigenesis by inducing ubiquitylation and degradation of rig-i [PDF]
, 2020 Glioblastoma multiforme (GB) is the most malignant primary brain tumor in humans, with an overall survival of approximatively 15 months. The molecular heterogeneity of GB, as well as its rapid progression, invasiveness and the occurrence of drug ...
Basili, I. +12 more
core +1 more source
Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway
Journal of Neuroinflammation, 2022 Highlights LPS-induced neuroinflammation promotes metabolic reprogramming. Neuroinflammation increased glycolytic flow and lactate release. Inhibitors of different glycolytic reactions prevented the inflammatory response. S100B changes suggest a role for
Adriana Fernanda K. Vizuete +8 more
doaj +1 more source
Frontiers in Psychology, 2015 Do we feel bound by our own misrepresentations? Does one act of cheating compel the cheater to make subsequent choices that maintain the false image even at a cost? To answer these questions we employed a two-task paradigm such that in the first task the participants could benefit from false reporting of private observations whereas in the second they ...
Avraham eMerzel +6 more
openaire +3 more sources