Results 51 to 60 of about 3,573,689 (297)
The interpretative options of anaphoric complex demonstratives
In this paper, we present experimental evidence from a ‘yes’/‘no’ judgement task and two acceptability rating studies (Experiments 1a-c) for the claim made in Hinterwimmer (2019) that sentences with two anaphorically interpreted complex demonstratives ...
Stefan Hinterwimmer, Umesh Patil
doaj +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Many episodic memory studies have critically implicated the hippocampus in the rapid binding of sensory information from the perception of the external environment, reported by exteroception.
Randa eKassab +5 more
doaj +1 more source
Fox (2000) argues that a single principle, Rule H, can account for (i) Strong Crossover, (ii) the ban on using co-binding to sneak around Condition B, and (iii) the Dahl paradigm. The focus of this paper is Fox’s analysis of the Dahl paradigm.
Alex Drummond
doaj +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Fusobacterium spp. target human CEACAM1 via the trimeric autotransporter adhesin CbpF
Neisseria meningitidis, Haemophilus influenzae, and Moraxella catarrhalis are pathogenic bacteria adapted to reside on human respiratory mucosal epithelia.
Matthew L. Brewer +5 more
doaj +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Behavioral and neuro-functional consequences of eliminating the KCNQ3 GABA binding site in mice
Voltage-gated potassium (Kv) channels formed by α subunits KCNQ2-5 are important in regulating neuronal excitability. We previously found that GABA directly binds to and activates channels containing KCNQ3, challenging the traditional understanding of ...
Kiki J. Chen +8 more
doaj +1 more source
DNA-binding residues and binding mode prediction with binding-mechanism concerned models [PDF]
Protein-DNA interactions are essential for fundamental biological activities including DNA transcription, replication, packaging, repair and rearrangement. Proteins interacting with DNA can be classified into two categories of binding mechanisms - sequence-specific and non-specific binding. Protein-DNA specific binding provides a mechanism to recognize
Oyang Yen-Jen +4 more
openaire +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source

