Results 81 to 90 of about 8,384,443 (422)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
An interview with Paul Binding [PDF]
, 2015 Paul Binding is a British writer who has worked in many fields: he is a literary critic, novelist, reviewer and renowned expert in Scandinavian literature.
Paul Binding, Turner, Nick
core
The hepta-β-glucoside elicitor-binding proteins from legumes represent a putative receptor family [PDF]
, 2000 The ability of legumes to recognize and respond to β-glucan elicitors by synthesizing phytoalexins is consistent with the existence of a membrane-bound β-glucan-binding site.
Ebel, J. +4 more
core +1 more source
Early Events in Japanese Encephalitis Virus Infection: Viral Entry
Pathogens, 2018 Japanese encephalitis virus (JEV), a mosquito-borne zoonotic flavivirus, is an enveloped positive-strand RNA virus that can cause a spectrum of clinical manifestations, ranging from mild febrile illness to severe neuroinvasive disease.
Sang-Im Yun, Young-Min Lee
doaj +1 more source
How do Language Models Bind Entities in Context? [PDF]
arXiv, 2023 To correctly use in-context information, language models (LMs) must bind entities to their attributes. For example, given a context describing a "green square" and a "blue circle", LMs must bind the shapes to their respective colors. We analyze LM representations and identify the binding ID mechanism: a general mechanism for solving the binding problem,
arxiv
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
The Interpretation of Pronouns across Spanish-Speaking Populations
Languages, 2018 In this paper, we will present data from both Spanish acquisition and aphasia on the Pronoun Interpretation Problem (PIP), according to which children allow pronouns to be identified with local c-commanding antecedents.
Sergio Baauw
doaj +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Information Extraction Techniques for the Purposes of Semantic Indexing of Archaeological Resources [PDF]
, 2013 The paper describes the use of Information Extraction (IE), a Natural Language Processing (NLP) technique to assist ‘rich’ semantic indexing of diverse archaeological text resources.
Binding, C, Tudhope, D, Vlachidis, A
core
Activation mechanism of ATP-sensitive K+ channels explored with real-time nucleotide binding
eLife, 2019 The response of ATP-sensitive K+ channels (KATP) to cellular metabolism is coordinated by three classes of nucleotide binding site (NBS). We used a novel approach involving labeling of intact channels in a native, membrane environment with a non ...
Michael Puljung +3 more
doaj +1 more source