Results 151 to 160 of about 1,463,984 (318)

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Benchmarking Zinc-Binding Site Predictors: A Comparative Analysis of Structure-Based Approaches. [PDF]

J Chem Inf Model
Ciofalo C, Laveglia V, Andreini C, Rosato A.   +3 more
europepmc   +1 more source

Studies of the oxygen binding site of cytochrome P-450. Nitric oxide as a spin-label probe.

, 1978
David H. O’Keeffe, Richard E. Ebel, J. A. Peterson   +2 more
openalex   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Role of the CTCF binding site in Human T-Cell Leukemia Virus-1 pathogenesis. [PDF]

PLoS Pathog
Joseph A, Cheng X, Harding J, Al-Saleem J, Green P, Griffith M, Veis D, Rauch DA, Ratner L.   +8 more
europepmc   +1 more source

Cytochalasin B binding proteins in human erythrocyte membranes. Modulation of glucose sensitivity by site interaction and partial solubilization of binding activities.

, 1978
Harold B. Pinkofsky, Amrit L. Rampal, M. Cowden, Chan Y. Jung   +3 more
openalex   +1 more source

Characterization of the integration protein of bacteriophage lambda as a site-specific DNA-binding protein. [PDF]

, 1977
Michael L. Kotewicz, Sung Won Chung, Yoshinori Takeda, Harrison Echols   +3 more
openalex   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

LncRNA SLNCR phenocopies the E2F1 DNA binding site to promote melanoma progression. [PDF]

Cell Rep
Shah K, Anastasakou E, Sejour L, Wang Y, Wert-Lamas L, Rauchet C, Studer S, Goller S, Distel RJ, Marasco W, Perera L, Vlachos IS, Novina CD.   +12 more
europepmc   +1 more source

Two substrate binding sites on tryptophanyl transfer ribonucleic acid synthetase of Escherichia coli.

, 1976
Karl H. Muench
openalex   +1 more source