Results 181 to 190 of about 2,892,311 (358)

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Solvation Energetic Costs of Cognate Binding Site Formation. [PDF]

J Chem Inf Model
Ji Y, Molino V, Ramsey S, Kurtzman T.
europepmc   +1 more source

Identification of a tyrosine residue at a nucleotide binding site in the beta subunit of the mitochondrial ATPase with p-fluorosulfonyl[14C]-benzoyl-5'-adenosine.

, 1978
Frederick Esch, W S Allison
openalex   +1 more source

Characterization of the integration protein of bacteriophage lambda as a site-specific DNA-binding protein. [PDF]

, 1977
Michael L. Kotewicz, Sung Won Chung, Yoshinori Takeda, Harrison Echols   +3 more
openalex   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

HolomiRA: a reproducible pipeline for miRNA binding site prediction in microbial genomes. [PDF]

BMC Bioinformatics
Bruscadin JJ, Cardoso TF, Conteville LC, da Silva JV, Ibelli AMG, Pena GAC, Porto T, de Oliveira PSN, Andrade BGN, Zerlotini A, Regitano LCA.   +10 more
europepmc   +1 more source

Localization of the binding site for cell attachment in the alpha1(I) chain of collagen

, 1978
Hynda K. Kleinman, Ermona B. McGoodwin, George R. Martin, Robert J. Klebe, Peter P. Fietzek, David E. Woolley   +5 more
openalex   +1 more source

Site of binding of mouse IgG2b to the Fc receptor on mouse macrophages. [PDF]

, 1979
Betty Diamond, Barbara K. Birshtein, Matthew D. Scharff   +2 more
openalex   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Isoxazole-Based Compounds Targeting the Taxane-Binding Site of Tubulin. [PDF]

Arch Pharm (Weinheim)
Peřina M, Kiss MA, Bělíček J, Vojáčková V, Veselá D, Minorics R, Zupko I, Frank É, Jorda R.   +8 more
europepmc   +1 more source