NyxBind: enhancing deep neural representations for transcription factor binding site prediction via contrastive learning. [PDF]
Yang X +7 more
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Isoxazole-Based Compounds Targeting the Taxane-Binding Site of Tubulin. [PDF]
Peřina M +8 more
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Cheminformatic analysis of protein surfaces provides binding site insights and informs identification strategies. [PDF]
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Structural Mapping of Surveillance Data Reveals Conservation of NNI Binding Site in RSV L Protein. [PDF]
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Anti-cancer drugs targeting the NADH-binding site of VDAC rewire channel electrophysiology and partially suppress cation selectivity. [PDF]
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HolomiRA: a reproducible pipeline for miRNA binding site prediction in microbial genomes. [PDF]
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Localization of the binding site on fibrin for the secondary binding site of thrombin
Biochemistry, 1988Affinity chromatography of active site inhibited thrombin on immobilized fragments derived from the central (desAB-NDSK) and terminal (D1) globular domains of fibrinogen revealed that the site responsible for the binding of thrombin at its secondary fibrin binding site is located in the central domain.
Z, Vali, H A, Scheraga
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Benzodiazepine-Binding Site and Gaba-Binding Site
1983There is a body of experimental evidence to suggest that the benzodiazepine-binding site, the GABA-binding site and the chloride ionophore are functionally correlated. To elucidate this issue, the interactions among these components in both membrane-bound state and soluble state are examined.
Li-ren Chang, Eric A. Barnard
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Cryptophycin 1 is a new cytotoxic antimicrotubule agent with excellent antitumor activity. The methods of Sackett (Biochemistry, 34, 7010-7019, 1995), utilizing the selective and specific proteolysis of alpha- and beta-tubulin by trypsin and chymotrypsin, was used to identify the cryptophycin 1 binding site on tubulin.
S L, Mooberry, C R, Taoka, L, Busquets
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This chapter assesses advances in the understanding and manipulation of antibody binding sites and variable regions. The antigen binding region of an antibody reduced to a 25-kDa minimum comprises of a noncovalent heterodimer of V H and V L domains.
J S, Huston, M N, Margolies, E, Haber
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