Results 201 to 210 of about 1,655,478 (266)

Isoxazole-Based Compounds Targeting the Taxane-Binding Site of Tubulin. [PDF]

open access: yesArch Pharm (Weinheim)
Peřina M   +8 more
europepmc   +1 more source

Structural Mapping of Surveillance Data Reveals Conservation of NNI Binding Site in RSV L Protein. [PDF]

open access: yesPathogens
Patel R   +6 more
europepmc   +1 more source

HolomiRA: a reproducible pipeline for miRNA binding site prediction in microbial genomes. [PDF]

open access: yesBMC Bioinformatics
Bruscadin JJ   +10 more
europepmc   +1 more source

Localization of the binding site on fibrin for the secondary binding site of thrombin

Biochemistry, 1988
Affinity chromatography of active site inhibited thrombin on immobilized fragments derived from the central (desAB-NDSK) and terminal (D1) globular domains of fibrinogen revealed that the site responsible for the binding of thrombin at its secondary fibrin binding site is located in the central domain.
Z, Vali, H A, Scheraga
openaire   +2 more sources

Benzodiazepine-Binding Site and Gaba-Binding Site

1983
There is a body of experimental evidence to suggest that the benzodiazepine-binding site, the GABA-binding site and the chloride ionophore are functionally correlated. To elucidate this issue, the interactions among these components in both membrane-bound state and soluble state are examined.
Li-ren Chang, Eric A. Barnard
openaire   +1 more source

Cryptophycin 1 binds to tubulin at a site distinct from the colchicine binding site and at a site that may overlap the vinca binding site

Cancer Letters, 1996
Cryptophycin 1 is a new cytotoxic antimicrotubule agent with excellent antitumor activity. The methods of Sackett (Biochemistry, 34, 7010-7019, 1995), utilizing the selective and specific proteolysis of alpha- and beta-tubulin by trypsin and chymotrypsin, was used to identify the cryptophycin 1 binding site on tubulin.
S L, Mooberry, C R, Taoka, L, Busquets
openaire   +2 more sources

Antibody Binding Sites

1996
This chapter assesses advances in the understanding and manipulation of antibody binding sites and variable regions. The antigen binding region of an antibody reduced to a 25-kDa minimum comprises of a noncovalent heterodimer of V H and V L domains.
J S, Huston, M N, Margolies, E, Haber
openaire   +2 more sources

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