Photoaffinity site-specific covalent labeling of human corticosteroid-binding globulin. [PDF]
Diana Marver +3 more
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Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Targeting the RAGE-RIPK1 binding site attenuates diabetes-associated cognitive deficits. [PDF]
Gao L +13 more
europepmc +1 more source
Carboxymethylation of methionine residues in bovine pituitary luteinizing hormone and its subunits. Effects on the binding activity with receptor sites and interactions between subunits [PDF]
K. W. Cheng
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Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
Revealing the location and dynamics of a concealed binding site in the dopamine transporter. [PDF]
Zhu R +22 more
europepmc +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
PrankWeb 4: a modular web server for protein-ligand binding site prediction and downstream analysis. [PDF]
Polák L +5 more
europepmc +1 more source
Inducible and constitutive nucleoside-binding sites in Escherichia coli: differential inhibition by nucleoside analogues [PDF]
J. Doskočil, Antonı́n Holý
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