Results 101 to 110 of about 5,097,951 (211)

In Silico Analysis of miRNA-mRNA Binding Sites in Arabidopsis thaliana as a Model for Drought-Tolerant Plants

open access: yesPlants
Drought stress limits plant survival and yield in arid regions. Uncovering the molecular mechanisms of drought tolerance is key to developing resilient crops.
Yryszhan Zhakypbek   +9 more
doaj   +1 more source

Systematic exploration of multiple drug binding sites

open access: yesJournal of Cheminformatics, 2017
Background Targets with multiple (prerequisite or allosteric) binding sites have an increasing importance in drug design. Experimental determination of atomic resolution structures of ligands weakly bound to multiple binding sites is often challenging ...
Mónika Bálint   +4 more
doaj   +1 more source

Guanine nucleotides regulate 2-[125I]Iodomelatonin binding sites in chick retinal pigment epithelium but not in neuronal retina

open access: yes, 1991
The characteristics of the binding sites labeled by the radioligand 2-[125I]iodomelatonin were compared in chicken neuronal retina and retinal pigment epithelium (RPE).
Nelson W. S. Chong   +3 more
core   +1 more source

Features of binding sites for Pch and Ler.

open access: yes, 2016
A. Overlapping of binding sites. Binding sites for Ler and Pch are classified by overlapping with H-NS bindings and Pch or Ler bindings. B. G+C contents of binding sites for H-NS, Pch, and Ler.
Taku Oshima (78580)   +4 more
core   +1 more source

Discrimination between RNA binding sites and DNA binding sites.

open access: yes, 2015
For DNA binding site prediction programs, DNA binding sites (3.5Å as distance cutoff) from a data set are taken as positive while RNA binding sites from another data set are taken as negative, the AUC values of these discriminations are plotted with ...
Eric Westhof (11340)   +1 more
core   +1 more source

Computational identification of uncharacterized cruzain binding sites.

open access: yesPLoS Neglected Tropical Diseases, 2010
Chagas disease, caused by the unicellular parasite Trypanosoma cruzi, claims 50,000 lives annually and is the leading cause of infectious myocarditis in the world.
Jacob D Durrant   +3 more
doaj   +1 more source

AFFINITY LABELING OF ADENOSINE-A1 BINDING-SITES

open access: yes, 1987
The adenosine A1 receptors of sheep brain membranes have been identified by the specific binding of radiolabeled cyclohexyl[3H]adenosine ([3H]CHA). Pretreatment of membranes with periodate-oxidized CHA causes a dose- and time-dependent decrease in the ...
MARTINI, CLAUDIA   +3 more
core   +1 more source

Polyphenol Interactions with Amyloid Fibrils: A Molecular Docking Study

open access: yesEast European Journal of Physics
Polyphenols, a versatile group of naturally occurring compounds with many favorable biological properties currently attract increasing research interest in the context of their ability to inhibit the formation and to destabilize special protein ...
Uliana Malovytsia   +5 more
doaj   +1 more source

Repetitive and Overlapping Binding Sites

open access: yes, 2013
(A) Histogram of the number of binding sites responsible for each interaction between a TF and an operon, according to the EcoCyc database [8]. Note that multiple sites are common; the cis-regulatory region of focA, e.g., has as many as 11 binding sites ...
Sander Tans (219198)   +2 more
core   +1 more source

EFFECT OF FLANKING SEQUENCES ON THE ACCURACY OF THE RECOGNITION OF TRANSCRIPTION FACTOR BINDING SITES

open access: yesВавиловский журнал генетики и селекции, 2015
The development of in vitro methods produced new experimental information on protein binding to DNA, which is accumulated in databases and used in studies of mechanisms regulating gene expression and in the development of computer-assisted methods of ...
T. M. Khlebodarova   +7 more
doaj  

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