Results 81 to 90 of about 5,097,951 (211)

Conservative domains of amino acids of PKS3, including 3-ketoacyl synthetase enzyme domain (KS), acyltransferase enzyme domain (FabD), 3-ketoacyl-ACP reductase enzyme domain (KR), dehydratase enzyme domain (DH) and thirteen phosphopantetheine-binding sites (pp-binding site).

, 2018
Conservative domains of amino acids of PKS3, including 3-ketoacyl synthetase enzyme domain (KS), acyltransferase enzyme domain (FabD), 3-ketoacyl-ACP reductase enzyme domain (KR), dehydratase enzyme domain (DH) and thirteen phosphopantetheine-binding ...
Zhendong Wang (578111), Yalin Guo (6069341), Xuexue Cao (6069338), Qin Yang (25816), Chunhong Pang (6069347), Deguang Sun (1538362), Feng Zhang (6548), Pan Hou (6069344), Zhu Liu (646037), Xiaonan Zang (3704794), Chang Liu (35901)   +10 more
core   +1 more source

Predicting the biological activity of selected phytochemicals in Alsophila spinulosa leaves against 4-aminobutyrate-aminotransferase: A potential antiepilepsy agents

Eclética Química
The use of medicinal plants as an alternative mean of treating various diseases has drawn the attention of several researchers. The desire to find lasting solutions to epilepsy among humans increases every day.
Oyebamiji Abel Kolawole, Olujinmi Faith Eniola, Akintelu Sunday Adewale, Adetuyi Babatunde, Ogunlana Olubanke, Semire Banjo, Akintayo Emmanuel Temitope, Akintayo Cecilia Olufunke, Babalola Jonathan Oyebamiji, Olawoye Bolanle Mary, Aworinde Juliana Oluwasayo   +10 more
doaj   +1 more source

Wellington : a novel method for the accurate identification of digital genomic footprints from DNase-seq data [PDF]

, 2013
The expression of eukaryotic genes is regulated by cis-regulatory elements such as promoters and enhancers, which bind sequence-specific DNA-binding proteins.
Bonifer, Constanze, Piper, Jason, Cockerill, Peter N., Elze, Markus C., Cockerill, Peter N, Bonifer, Constanze; id_orcid, Ott, Sascha, Elze, Markus C, Cauchy, Pierre   +8 more
core   +1 more source

High-Mobility-Group protein I can modulate binding of transcription factors to the U5 region of the human immunodeficiency virus Type 1 proviral promoter [PDF]

, 2000
HMG I/Y appears to be a multifunctional protein that relies on in its ability to interact with DNA in a structure-specific manner and with DNA, binding transcriptional activators via distinct protein-protein interaction surfaces.
Henderson, A., Tremethick, D.J., Siddon, N., Reeves, R., Bunce, M.   +4 more
core  

The predicted DNA/RNA-binding sites and protein binding sites of RCA_L and RCA_S.

, 2015
(A) The predicted RCAS sites. (B) The predicted RCAL sites. Dots indicate the DNA/RNA-binding sites, and the rhombus indicates the protein binding sites.
Xiao-Man Wang (815526), Yan-Hua Qi (815527), De-An Jiang (815528), Yue Chen (73753), Dun Wang (525747), Li Zhou (54356), Yi He (408132)   +6 more
core   +1 more source

Many locks to one key: N-acetylneuraminic acid binding to proteins

IUCrJ
Sialic acids play crucial roles in cell surface glycans of both eukaryotic and prokaryotic organisms, mediating various biological processes, including cell–cell interactions, development, immune response, oncogenesis and host–pathogen interactions. This
KanagaVijayan Dhanabalan, YiYang Cheng, Trung Thach, Ramaswamy Subramanian   +3 more
doaj   +1 more source

Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain [PDF]

, 2005
Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species. The rules that govern calpain specificity have not yet been determined.
Mann, Karlheinz, Mann, K., Ghosh, M., Machleidt, W., Machleidt, Werner, Siwanowicz, I., Ghosh, Madhumita, Holak, Tad A., Holak, T., Siwanowicz, Igor, Shanker, Sreejesh, Shanker, S.   +11 more
core   +1 more source

Structural Analysis of the Drosophila melanogaster GSTome

Biomolecules
Glutathione transferase (GST) is a superfamily of ubiquitous enzymes, multigenic in numerous organisms and which generally present homodimeric structures.
Nicolas Petiot, Mathieu Schwartz, Patrice Delarue, Patrick Senet, Fabrice Neiers, Adrien Nicolaï   +5 more
doaj   +1 more source

Return of the Electric Binding Site [PDF]

The Journal of General Physiology, 2008
The BK-type Ca2+-activated K+ channel has been the subject of increasingly detailed mechanistic study since the first recordings of this channel were obtained more than 25 years ago (Pallotta et al., 1981; Latorre et al., 1982; Magleby, 2003; and references therein).
openaire   +2 more sources

In Silico Analysis of C₆₀ Fullerene Interaction with TMPRSS2: Toward Novel COVID-19 Prevention Approaches

Molecules
The recent global spread of the SARS-CoV-2 pathogen, which causes COVID-19, and its rapid mutation, requires the fast development of effective preventive and treatment measures.
Vasyl Hurmach, Viacheslav Karaushu, Svitlana Prylutska, Zinaida Klestova, Sergiy Vyzhva, Yuriy Prylutskyy, Uwe Ritter, Vasil Garamus   +7 more
doaj   +1 more source