Results 61 to 70 of about 5,097,951 (211)

The ontogeny of 2-[125I]iodomelatonin binding sites in chicken brain

, 1992
The characteristics of the binding sites for 2-[125I]iodomelatoion in were studied in chicken brain membranes during development. Specific binding, defined using cold melatonin (1 μM), was detected as early as 8-day-old embryos.
Chong, Nelson W., Sugden, D.
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Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme

Molecules
The COVID-19 pandemic, driven by the novel coronavirus SARS-CoV-2, has drastically reshaped global health and socioeconomic landscapes. The papain-like protease (PLpro) plays a critical role in viral polyprotein cleavage and immune evasion, making it a ...
Ann Varghese, Jie Liu, Bailang Liu, Wenjing Guo, Fan Dong, Tucker A. Patterson, Huixiao Hong   +6 more
doaj   +1 more source

Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA

Cell Reports, 2017
Jasmonates (JAs) are essential plant hormones that play important roles in the regulation of plant growth and the response to environmental stress. In the JA signaling pathway, the core transcription factors are a class of basic helix-loop-helix (bHLH ...
Teng-fei Lian, Yong-ping Xu, Lan-fen Li, Xiao-Dong Su   +3 more
doaj   +1 more source

Direct determination of unbound lipophilic ligands in aqueous solutions [PDF]

Biological Procedures Online, 2004
Due to their hydrophobic nature, lipophilic compounds are always bound to proteins when transported in the organism. The transfer of such compounds between their binding proteins and cells as well as intracellular trafficking is mediated by a very low ...
Bojesen Inge N.
doaj   +1 more source

Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces [PDF]

, 2004
The regulators of complement activation (RCA) are critical to health and disease because their role is to ensure that a complement-mediated immune response to infection is proportionate and targeted.
Krystyna Bromek, Uhrin, D, O'Leary, JM, Xuefeng Wang, Stanislava Uhrinova, Joanne M. O'Leary, Black, GM, Wang, XF, Malgorzata Krych, John P. Atkinson, Uhrinova, S, Dusan Uhrin, Atkinson, JP, Gordon M. Black, Krych, M, Schmitz, C, Paul N. Barlow, Bromek, K, Barlow, PN, Christian Schmitz   +19 more
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Inferring binding specificities of human transcription factors with the wisdom of crowds

Cell Reports
Summary: DNA motif discovery and, particularly, computational modeling of transcription factor binding motifs, has been a mecca of algorithmic bioinformatics for several decades.
Nikita Gryzunov, Dmitry Penzar, Vasilii Kamenets, Valery Vyaltsev, Ivan Kozin, Irina A. Eliseeva, Vladimir Nozdrin, Ilya E. Vorontsov, Sergey Bushuev, Vadim Strekalovskikh, Arsenii Zinkevich, Gregory Andrews, Matwej Bedarew, Ido Blass, Dmitry Frolov, Iuliia Lariushina, Jill Moore, Yaron Orenstein, German Roev, Danil Salimov, Noam Shimshoviz, Ido Tziony, Zhiping Weng, Philipp Bucher, Bart Deplancke, Oriol Fornes, Jan Grau, Ivo Grosse, Arttu Jolma, Fedor A. Kolpakov, Vsevolod J. Makeev, Timothy R. Hughes, Ivan V. Kulakovskiy   +32 more
doaj   +1 more source

Characterization and Stability of the Antimony-Quercetin Complex [PDF]

Advanced Pharmaceutical Bulletin, 2019
Purpose: Quercetin is a flavonoid known for its therapeutic properties and for forming complexes. Although the antimony-quercetin (SbQ) complex has been produced before, no previous exploration of its characteristics has been published in literature ...
Valcilaine Teixeira Barbosa, Janaína Barros de Menezes, Josué Carinhanha Caldas Santos, Maria Lysete de Assis Bastos, João Xavier de Araújo-Júnior, Ticiano Gomes do Nascimento, Irinaldo Diniz Basílio-Júnior, Luciano Aparecido Meireles Grillo, Camila Braga Dornelas   +8 more
doaj   +1 more source

binding site [PDF]

, 2014
Citation: 'binding site' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.B00649 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Plant Hormone Binding Sites [PDF]

Annals of Botany, 2004
Receptors for plant hormones are becoming identified with increasing rapidity, although a frustrating number remain unknown. There have also been many more hormone-binding proteins described than receptors. This Botanical Briefing summarizes what has been discovered about hormone binding sites, their discovery and descriptions, and will not dwell on ...
openaire   +2 more sources

Analysis of shape, properties and "druggability" of protein binding pockets [PDF]

, 2009
Kenntnisse über die dreidimensionale Struktur therapeutisch relevanter Zielproteine bieten wertvolle Informationen für den rationalen Wirkstoffentwurf.
Weisel, Martin
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