Results 121 to 130 of about 2,663,361 (333)

Many locks to one key: N-acetylneuraminic acid binding to proteins

IUCrJ
Sialic acids play crucial roles in cell surface glycans of both eukaryotic and prokaryotic organisms, mediating various biological processes, including cell–cell interactions, development, immune response, oncogenesis and host–pathogen interactions. This
KanagaVijayan Dhanabalan, YiYang Cheng, Trung Thach, Ramaswamy Subramanian   +3 more
doaj   +1 more source

Predicting protein-protein binding sites in membrane proteins

BMC Bioinformatics, 2009
Background Many integral membrane proteins, like their non-membrane counterparts, form either transient or permanent multi-subunit complexes in order to carry out their biochemical function.
Bordner Andrew J
doaj   +1 more source

ORegAnno: an open access database and curation system for literature-derived promoters, transcription factor binding sites and regulatory variation [PDF]

, 2006
Stephen B. Montgomery, Obi L. Griffith, Monica C. Sleumer, Casey Bergman, Misha Bilenky, Erin Pleasance, Yuliya Prychyna, X. Zhang, Steven J.M. Jones   +8 more
openalex   +1 more source

Stabilization of Guest Molecules inside Cation‐Lidded Cucurbiturils Reveals that Hydration of Receptor Sites Can Impede Binding

, 2023
Suhang He, Bing Huang, Bohuai Xiao, Shuai Chang, Marina Podalko, Werner M. Nau   +5 more
openalex   +1 more source

Voronoi binding site models [PDF]

Journal of Computational Chemistry, 1987
AbstractA frequently occurring problem in drug design and enzymology is that the binding constants for several compounds to the same site are known, but the geometry and energetic interactions of the site are not. This paper presents in detail a novel approach to the problem which accurately but compactly represents the allowed conformation space of ...
openaire   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

High-throughput identification of interacting protein-protein binding sites

BMC Bioinformatics, 2007
Background With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces.
Wang Wei, Chung Jo-Lan, Bourne Philip E
doaj   +1 more source

Identification of the TRiC/CCT Substrate Binding Sites Uncovers the Function of Subunit Diversity in Eukaryotic Chaperonins [PDF]

, 2006
Christoph Spiess, Erik J. Miller, Amie J. McClellan, Judith Frydman   +3 more
openalex   +1 more source

The Hydrophobic Ligands Entry and Exit from the GPCR Binding Site-SMD and SuMD Simulations [PDF]

, 2020
Jakub Jakowiecki, Urszula Orzeł, Sathapana Chawananon, Przemysław Miszta, Sławomir Filipek   +4 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source