Results 131 to 140 of about 8,224,245 (384)
High-affinity binding sites involved in the import of porin into mitochondria [PDF]
, 1987 The specific recognition by mitochondria of the precursor of porin and the insertion into the outer membrane were studied with a radiolabeled water-soluble form of porin derived from the mature protein.
Neupert, Walter, Pfaller, Rupert
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Metal-binding sites of concanavalin A and their role in the binding of α-methyl
, 1968 A. Joseph Kalb, Alexander Levitzki
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Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
THE SITE OF BINDING OF PYRIDOXAL-5′-PHOSPHATE TO HEAR GLUTAMIC-ASPARTIC TRANSAMINASE [PDF]
, 1962 R.C. Hughes +2 more
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Voronoi binding site models [PDF]
Journal of Computational Chemistry, 1987 AbstractA frequently occurring problem in drug design and enzymology is that the binding constants for several compounds to the same site are known, but the geometry and energetic interactions of the site are not. This paper presents in detail a novel approach to the problem which accurately but compactly represents the allowed conformation space of ...
openaire +3 more sources
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
On the nature of two ribosomal sites for specific sRNA binding. [PDF]
, 1967 Kazuei Igarashi, Akira Kaji
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Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain
Journal of Neuroscience, 1985 N-methyl-D-aspartate (NMDA) is an acidic amino acid which depolarizes neurons by selectively interacting with a distinct class of excitatory amino acid receptor.
D. Monaghan, C. Cotman
semanticscholar +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Effect of cell density on thrombin binding to a specific site on bovine vascular endothelial cells. [PDF]
, 1981 We studied thrombin binding to proliferating and confluent endothelial cells derived from bovine vascular endothelium. [125]thrombin was incubated with nonconfluent or confluent endothelial cells and both the total amount bound and the amount linked in a
Gospodarowicz, D +3 more
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