Results 171 to 180 of about 1,402,076 (343)

CryptoBench: cryptic protein-ligand binding sites dataset and benchmark. [PDF]

Bioinformatics
Škrhák V, Novotný M, Feidakis CP, Krivák R, Hoksza D.   +4 more
europepmc   +1 more source

Studies of the oxygen binding site of cytochrome P-450. Nitric oxide as a spin-label probe.

, 1978
David H. O’Keeffe, Richard E. Ebel, J. A. Peterson   +2 more
openalex   +1 more source

Stimulation of hepatic mitochondrial alpha-glycerophosphate dehydrogenase and malic enzyme by L-triiodothyronine. Characteristics of the response with specific nuclear thyroid hormone binding sites fully saturated. [PDF]

, 1977
J H Oppenheimer, Ermelinda Santos Silva, Harold L. Schwartz, Martin I. Surks   +3 more
openalex   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

PinMyMetal: a hybrid learning system to accurately model transition metal binding sites in macromolecules. [PDF]

Nat Commun
Zhang H, Zhong J, Gucwa M, Zhang Y, Ma H, Deng L, Mao L, Minor W, Wang N, Zheng H.   +9 more
europepmc   +1 more source

Cytochalasin B binding proteins in human erythrocyte membranes. Modulation of glucose sensitivity by site interaction and partial solubilization of binding activities.

, 1978
Harold B. Pinkofsky, Amrit L. Rampal, M. Cowden, Chan Y. Jung   +3 more
openalex   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Comparative evaluation of methods for the prediction of protein-ligand binding sites. [PDF]

J Cheminform
Utgés JS, Barton GJ.
europepmc   +1 more source

Two substrate binding sites on tryptophanyl transfer ribonucleic acid synthetase of Escherichia coli.

, 1976
Karl H. Muench
openalex   +1 more source

Evidence That Tetrodotoxin and Saxitoxin Act at a Metal Cation Binding Site in the Sodium Channels of Nerve Membrane [PDF]

, 1974
Richard A. Henderson, J. M. Ritchie, Gary R. Strichartz   +2 more
openalex   +1 more source