Results 231 to 240 of about 1,606,399 (268)

The taxonomy of binding sites in proteins

Molecular and Cellular Biochemistry, 1978
Conservation of polypeptide fold and mode of ligand binding is frequently found within proteins of related function. Examples illustrating this phenomenon are taken from NAD linked enzymes, nucleotide binding proteins, polysaccharide binding proteins, heme binding proteins and enzymes with essential Fe--S complexes or zinc atoms.
M G, Rossmann, P, Argos
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Hydrophobic binding site in acetylcholinesterase

Journal of Medicinal Chemistry, 1975
The dissociation constants have been determined and compared for a series of reversible, noncovalent inhibitors of eel acetylcholinesterase that are structurally related to the very potent inhibitor, 1,2,3,4-tetrahydro-9-aminoacridine (THA).
George M. Steinberg, Morton L. Mednick, Jan Maddox, Robert Rice, Joyce Cramer   +4 more
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Localization of the Chaperone Binding-Site

Biochemical and Biophysical Research Communications, 1993
The hypothesis derived from models of the multi-oligomeric chaperone complex suggests that partially denatured proteins bind in a central cavity in the aggregate. To test this hypothesis, the molecular chaperone, alpha crystallin, was bound to partially denatured forms of gamma crystallin, and the binding site was visualized by immunogold localization.
D, Boyle, S, Gopalakrishnan, L, Takemoto
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Peripheral benzodiazepine binding sites

Pharmacology & Therapeutics, 1989
Article de synthese sur les sites de fixation peripheriques des benzodiazepines: distribution, fixation biologique, action au niveau du systeme nerveux central, regulation par le GABA et le stress, regulation endocrine, relation avec les canaux calcium, autres ligands, role ...
V, Saano, L, Rägo, M, Räty
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Echinomycin Binding Sites on DNA

Science, 1984
The preferred binding sites of echinomycin on DNA can be determined by a method called "footprinting." A 32 P end-labeled restriction fragment from pBR322 DNA is protected by binding to echinomycin, and cleaved by a synthetic DNA cleaving reagent, methidiumpropyl--EDTA⋅Fe(II); the DNA cleavage products are then ...
Van Dyke, Michael M., Dervan, Peter B.
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The Ribosome Binding Site Calculator

2011
The Ribosome Binding Site (RBS) Calculator is a design method for predicting and controlling translation initiation and protein expression in bacteria. The method can predict the rate of translation initiation for every start codon in an mRNA transcript.
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MEASUREMENT OF TESTOSTERONE BINDING SITES

Acta Endocrinologica, 1970
ABSTRACT A Sephadex assay technique, in use in our laboratory for the study of steroid-protein interactions, allows expression of the molar concentration of a testosterone-binding component of human serum of high binding affinity in terms of the molar concentration of testosterone-binding sites: examples with model calculations are provided ...
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Three binding sites on t-PA: Lysine binding sites (LBS), fibrinogen) binding site and a site to bind to LBS

Fibrinolysis, 1989
T. Urano, K. Sakakibara, Y. Takada, A. Takeda   +3 more
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Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites

Nucleic Acids Research, 2021
Joan Frigola, Radhakrishnan Sabarinathan, Abel González-Pérez   +2 more
exaly  

Mapping cryptic binding sites of drug targets to overcome drug resistance

Drug Resistance Updates, 2023
Ge-Fei Hao
exaly