Results 281 to 290 of about 8,324,980 (383)

Determination of silver(I)-binding sites in canonical B-DNA by NMR spectroscopy. [PDF]

J Biol Inorg Chem
Lenz T, Javornik U, Hebenbrock M, Plavec J, Müller J.   +4 more
europepmc   +1 more source

The Location of the Repressor Binding Sites in the lac Operon

, 1974
William S. Reznikoff, Robert B. Winter, Carolyn Katovich Hurley   +2 more
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Preliminary assessment of the therapeutic potential of staphylococcal enterotoxin-like W via biological activity and TCR binding sites analysis. [PDF]

Virulence
Yang Y, Wei X, Meng F, Gong Y, Guo Y, Long L, Fan J, Zhao Y, Wang W, Xiao D, Wang L, Zhang M, Hu D, Zhang J, Yan X.   +14 more
europepmc   +1 more source

The nuclear envelope. The major site of insulin binding in rat liver nuclei.

, 1978
Riccardo Vigneri, Ira D. Goldfine, K. Y. Wong, George J. Smith, V. Pezzino   +4 more
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

CryptoBench: cryptic protein-ligand binding sites dataset and benchmark. [PDF]

Bioinformatics
Škrhák V, Novotný M, Feidakis CP, Krivák R, Hoksza D.   +4 more
europepmc   +1 more source

Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server

Nature Protocols, 2013
Heping Zheng, M. Chordia, D. Cooper, M. Chruszcz, Peter Müller, G. Sheldrick, W. Minor   +6 more
semanticscholar   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

CTCF: the protein, the binding partners, the binding sites and their chromatin loops

Philosophical Transactions of the Royal Society B: Biological Sciences, 2013
Sjoerd J. B. Holwerda, W. de Laat
semanticscholar   +1 more source