Results 151 to 160 of about 1,531,106 (344)

Short peptides containing Norbornene amino acid (NRB): role of the NRB scaffold in self-assembly

, 2016
A number of papers report on spontaneous assembly of peptides into ordered nanostructures with a variety of morphologies and this number is still expanding.[1] Besides the numerous advantages of using peptides as building blocks for different types of ...
S. Locarno, F. Clerici, S. Argentiere, A. Ruffoni, R. Soave   +4 more
core  

Identified bioactive peptides from literature.

, 2019
Identified bioactive peptides from literature.
Chunlei Liu (57542), Mingxian Geng (6612689), Ji Wang (137458), Li Fang (315274), Jingsheng Liu (4009946), Weihong Min (4009949)   +5 more
core   +1 more source

IDENTIFICATION OF MOTIFS IN BIOACTIVE PEPTIDES PRECURSORS

, 2020
In-silico study was carried out to study motifs present in precursors of antimicrobial, antithrombotic, casein derived and mineral binding bioactive peptides by using online servers.
Shrikant Sharma , Shashank Rana, Ravi Uniyal, Raghvendar Singh   +2 more
core   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Ghrelin is essential for lowering blood pressure during torpor

Frontiers in Endocrinology
IntroductionDaily torpor is an active hypothermic phenomenon that is observed in some mammals and birds during fasting. A decrease in blood pressure has also been observed in torpor; however, there remains a lack of knowledge of the underlying mechanism.
Kazuma Matsui, Takanori Ida, Kanae Oishi, Masayasu Kojima, Takahiro Sato   +4 more
doaj   +1 more source

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Anti-HIV-1 Activity of the Integrase Strand Transfer Inhibitor ACC017

Viruses
HIV-1 integrase strand transfer inhibitors (INSTIs) are pivotal to antiretroviral therapy. However, the emergence of drug-resistant mutations necessitates the development of new agents. Here, we present ACC017 as a novel INSTI candidate.
Meng-Di Ma, Rong-Hua Luo, Chun-Yan Li, Guan-Cheng Huang, Xin-Yan Long, Feng-Ying He, Liu-Meng Yang, He-Liang Fu, Yong-Tang Zheng   +8 more
doaj   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Bioactive peptides in dairy products.

, 2012
Bioactive peptides are hydrolysates with specific amino acid sequences that exert a positive physiological influence on the body. They are inert within the native protein, but once cleaved from the native protein by microbial or added enzymes and/or ...
Choi, J., Sabikhi, L.
core   +1 more source

A Tachyplesin Antimicrobial Peptide from Theraphosidae Spiders with Potent Antifungal Activity Against Cryptococcus neoformans

Microorganisms
The venoms of Theraphosidae spiders have evolved into diverse natural pharmacopeias through selective pressures. Cryptococcus neoformans is a global health threat that frequently causes life-threatening meningitis and fungemia, particularly in ...
Brenda B. Michira, Yi Wang, James Mwangi, Kexin Wang, Demeke Asmamaw, Dawit Adisu Tadese, Jinai Gao, Mehwish Khalid, Qiu-Min Lu, Ren Lai, Juan Li   +10 more
doaj   +1 more source