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Fluorinated Protein and Peptide Materials for Biomedical Applications [PDF]

open access: yesPharmaceuticals, 2022
Fluorination represents one of the most powerful modern design strategies to impart biomacromolecules with unique functionality, empowering them for widespread application in the biomedical realm.
Julia M. Monkovic   +3 more
doaj   +2 more sources

Formation mechanisms of chitosan-silica hybrid materials and its performance as solid support for KR-12 peptide adsorption: Impact on KR-12 antimicrobial activity and proteolytic stability

open access: yesJournal of Materials Research and Technology, 2020
Chitosan-silica materials offer a specific environment for the adsorption of biofunctional molecules, such as the antimicrobial peptide KR-12. The objective here is to rationalize the changes in the physicochemical properties of these chitosan-silica ...
Johnatan Diosa   +3 more
doaj   +3 more sources

Ultrashort Cationic Peptide Fmoc-FFK as Hydrogel Building Block for Potential Biomedical Applications

open access: yesGels, 2023
Fmoc-diphenylalanine (Fmoc-FF) is a low-molecular-weight peptide hydrogelator. This simple all-aromatic peptide can generate self-supporting hydrogel materials, which have been proposed as novel materials for diagnostic and pharmaceutical applications ...
Enrico Gallo   +9 more
doaj   +1 more source

Multicomponent Peptide-Based Hydrogels Containing Chemical Functional Groups as Innovative Platforms for Biotechnological Applications

open access: yesGels, 2023
Multicomponent hydrogels (HGs) based on ultrashort aromatic peptides have been exploited as biocompatible matrices for tissue engineering applications, the delivery of therapeutic and diagnostic agents, and the development of biosensors.
Sabrina Giordano   +9 more
doaj   +1 more source

Self-Supporting Hydrogels Based on Fmoc-Derivatized Cationic Hexapeptides for Potential Biomedical Applications

open access: yesBiomedicines, 2021
Peptide-based hydrogels (PHGs) are biocompatible materials suitable for biological, biomedical, and biotechnological applications, such as drug delivery and diagnostic tools for imaging.
Carlo Diaferia   +6 more
doaj   +1 more source

Incorporation of PEG Diacrylates (PEGDA) Generates Hybrid Fmoc-FF Hydrogel Matrices

open access: yesGels, 2022
Generated by a hierarchical and multiscale self-assembling phenomenon, peptide-based hydrogels (HGs) are soft materials useful for a variety of applications. Short and ultra-short peptides are intriguing building blocks for hydrogel fabrication.
Elisabetta Rosa   +9 more
doaj   +1 more source

Fmoc-Diphenylalanine Hydrogels: Optimization of Preparation Methods and Structural Insights

open access: yesPharmaceuticals, 2022
Hydrogels (HGs) are tri-dimensional materials with a non-Newtonian flow behaviour formed by networks able to encapsulate high amounts of water or other biological fluids.
Carlo Diaferia   +3 more
doaj   +1 more source

Fatty Acids/Tetraphenylethylene Conjugates: Hybrid AIEgens for the Preparation of Peptide-Based Supramolecular Gels

open access: yesFrontiers in Chemistry, 2022
Aggregation-induced emissive materials are gaining particular attention in the last decades due to their wide application in different fields, from optical devices to biomedicine.
Elisa Impresari   +10 more
doaj   +1 more source

Transition of Nano-Architectures Through Self-Assembly of Lipidated β3-Tripeptide Foldamers

open access: yesFrontiers in Chemistry, 2020
β3-peptides consisting exclusively of β3-amino acids adopt a variety of non-natural helical structures and can self-assemble into well-defined hierarchical structures by axial head-to-tail self-assembly resulting in fibrous materials of varying sizes and
Nathan Habila   +8 more
doaj   +1 more source

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