Results 31 to 40 of about 81,113 (295)

The Genus Chrysosporium: A Potential Producer of Natural Products

open access: yesFermentation, 2023
Chrysosporium, a genus of ascomycete fungi in the family Onygenaceae, has the ability to produce abundant new bioactive natural products, providing a structural foundation in drug development.
Yifei Wang   +4 more
doaj   +1 more source

Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]

open access: yes, 2012
Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Djafarzadeh, Roghieh   +10 more
core   +5 more sources

Structural Diversity and Biological Activities of Novel Secondary Metabolites from Endophytes

open access: yesMolecules, 2018
Exploration of structurally novel natural products greatly facilitates the discovery of biologically active pharmacophores that are biologically validated starting points for the development of new drugs.
Han Gao, Gang Li, Hong-Xiang Lou
doaj   +1 more source

Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]

open access: yes, 1991
" An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core   +1 more source

Chemical Composition and Bioactive Characterisation of Impatiens walleriana

open access: yesMolecules, 2021
The attractive colour characteristics of the flowers of the species Impatiens walleriana have been arousing great interest in the food industry, which is looking for potential natural sources of colouring ingredients.
Eleomar de O. Pires   +11 more
doaj   +1 more source

Bioactives and Inflammation

open access: yesCurrent Issues in Molecular Biology, 2023
Inflammation is one of the body’s most complex physiological defense mechanisms against harmful substances [...]
Guan-Ting Liu, Chan-Yen Kuo
openaire   +3 more sources

Synthesis Optimization of L-Aspartic acid β-hydroxamate by a novel Enzyme, β-Aspartyl-γ-glutamyl transferase [PDF]

open access: yes, 2015
L-Aspartic acid β-hydroxamate or L-β-Aspartyl hydroxamate (BAH), water soluble- chemical compound currently obtains popularity due to its role in several important biochemical processes and to its bioactivities.
Naohara, Ryosuke   +4 more
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Targeting PI3K signaling in Lung Cancer: advances, challenges and therapeutic opportunities

open access: yesJournal of Translational Medicine
Lung cancer remains the leading cause of cancer-related mortality globally, necessitating the continual exploration of novel therapeutic targets.
Bitian Zhang   +4 more
doaj   +1 more source

Artemisinin and Its Derivatives as Potential Anticancer Agents

open access: yesMolecules
Artemisinin is a natural sesquiterpene lactone obtained from the traditional Chinese medicinal herb Artemisia annua L. (qinghao). Artemisinin and its derivatives share an unusual endoperoxide bridge and are extensively used for malaria treatment ...
Luan Wen   +4 more
doaj   +1 more source

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