Results 31 to 40 of about 81,113 (295)
The Genus Chrysosporium: A Potential Producer of Natural Products
Chrysosporium, a genus of ascomycete fungi in the family Onygenaceae, has the ability to produce abundant new bioactive natural products, providing a structural foundation in drug development.
Yifei Wang +4 more
doaj +1 more source
Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]
Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Djafarzadeh, Roghieh +10 more
core +5 more sources
Structural Diversity and Biological Activities of Novel Secondary Metabolites from Endophytes
Exploration of structurally novel natural products greatly facilitates the discovery of biologically active pharmacophores that are biologically validated starting points for the development of new drugs.
Han Gao, Gang Li, Hong-Xiang Lou
doaj +1 more source
Lipopolysaccharide-specific acyloxyacyl hydrolase [PDF]
" An acyloxyacyl hydrolase from the human promyelocyte cell line HL-60 has been found to specifically hydrolyze fatty acids from their ester linkages to hydroxy groups of 3-hydroxyfatty acids, the latter being being bound in turn to lipopolysaccharide ...
Hall, Catherine L., Munford, Robert S.
core +1 more source
Chemical Composition and Bioactive Characterisation of Impatiens walleriana
The attractive colour characteristics of the flowers of the species Impatiens walleriana have been arousing great interest in the food industry, which is looking for potential natural sources of colouring ingredients.
Eleomar de O. Pires +11 more
doaj +1 more source
Inflammation is one of the body’s most complex physiological defense mechanisms against harmful substances [...]
Guan-Ting Liu, Chan-Yen Kuo
openaire +3 more sources
Synthesis Optimization of L-Aspartic acid β-hydroxamate by a novel Enzyme, β-Aspartyl-γ-glutamyl transferase [PDF]
L-Aspartic acid β-hydroxamate or L-β-Aspartyl hydroxamate (BAH), water soluble- chemical compound currently obtains popularity due to its role in several important biochemical processes and to its bioactivities.
Naohara, Ryosuke +4 more
core
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Targeting PI3K signaling in Lung Cancer: advances, challenges and therapeutic opportunities
Lung cancer remains the leading cause of cancer-related mortality globally, necessitating the continual exploration of novel therapeutic targets.
Bitian Zhang +4 more
doaj +1 more source
Artemisinin and Its Derivatives as Potential Anticancer Agents
Artemisinin is a natural sesquiterpene lactone obtained from the traditional Chinese medicinal herb Artemisia annua L. (qinghao). Artemisinin and its derivatives share an unusual endoperoxide bridge and are extensively used for malaria treatment ...
Luan Wen +4 more
doaj +1 more source

