Results 141 to 150 of about 469,546 (342)

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery

open access: yesAdvanced Materials, EarlyView.
This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae   +6 more
wiley   +1 more source

Synthesis of Tertiary Amine Assisted Cytocompatible Zn‐MOFs for Efficient Nucleic Acid Encapsulation and Delivery to Prostate Cancer Cells

open access: yesAdvanced Materials Interfaces, EarlyView.
The study explores the influence of a tertiary amine in loading genetic material in a hybrid composite. The study highlights how structural attributes and chemical composition govern the crystallinity and cytocompatibility of ZIF‐biocomposites that effectively deliver nucleic acid to cancer cells.
Shakil Ahmed Polash   +3 more
wiley   +1 more source

Absolute oral bioavailability of ciprofloxacin [PDF]

open access: green, 1986
George L. Drusano   +5 more
openalex   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao   +6 more
wiley   +1 more source

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