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Bioavailability of carotenoids [PDF]
Abstract
Castenmiller, J.J.M., West, C.E.
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The Bioavailability of Drugs—The Current State of Knowledge
Drug bioavailability is a crucial aspect of pharmacology, affecting the effectiveness of drug therapy. Understanding how drugs are absorbed, distributed, metabolized, and eliminated in patients’ bodies is essential to ensure proper and safe treatment ...
Marlena Stielow+5 more
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Flavonoid Bioavailability and Attempts for Bioavailability Enhancement [PDF]
Flavonoids are a group of phytochemicals that have shown numerous health effects and have therefore been studied extensively. Of the six common food flavonoid classes, flavonols are distributed ubiquitously among different plant foods whereas appreciable amounts of isoflavones are found in leguminous plant-based foods.
Surangi Thilakarathna, H. Rupasinghe
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Many active pharmaceutical ingredients show low oral bioavailability due to factors such as poor solubility and physical and chemical instability.
Álvaro Sarabia-Vallejo+4 more
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The achievement of optimal folate status to prevent neural-tube defects, and possibly other diseases, is hindered by the well-recognised incomplete bioavailability of the natural folates found in foods compared with the synthetic vitamin, folic acid.
Helene, McNulty, Kristina, Pentieva
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Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics
The low water solubility of pharmacoactive molecules limits their pharmacological potential, but the solubility parameter cannot compromise, and so different approaches are employed to enhance their bioavailability. Pharmaceutically active molecules with
Dixit V. Bhalani+3 more
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Polyphenols and Human Health: The Role of Bioavailability
Polyphenols are a group of phytochemicals with potential health-promoting effects. They are classified as flavonoid (flavonols, flavanols, flavones, flavanones, isoflavones, and anthocyanins) and non-flavonoid molecules (phenolic acids, hydroxycinnamic ...
Chiara Di Lorenzo+4 more
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The rate and extent (amount) of unmodified medication absorption from its dose form is referred to as bioavailability. It is one of the critical criteria for achieving optimal medication concentration in the systemic circulation. Bioavailability is a significant factor of a drug's therapeutic efficacy, which is determined by the drug's solubility in ...
Vaishnavi Tejram Gabhane+5 more
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Bioavailability of diphenylhydantoin [PDF]
A four‐way crossover study was performed in 8 adult volunteers using a Latin square design with 4 groups of 2 subiects arranged in order of increasing body weight. Single 100 mg doses of diphenylhydantoin (DPH) sodium were administered as an aqueous solution (treatment A), the innovator's capsule (treatment B), alld a commercially available generic ...
Albert, Kenneth S.+4 more
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Hesperidin and hesperetin are polyphenols that can be found predominantly in citrus fruits. They possess a variety of pharmacological properties such as neuroprotective and antidiabetic activity. However, the bioavailability of these compounds is limited
Kamil Wdowiak+4 more
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