Results 11 to 20 of about 803,201 (379)
Frontiers in Pharmacology, 2022 Cyclophosphamide (CP) is an anti-cancer alkylating prodrug, metabolized by CYP450 into its active metabolite 4-hydroxycyclophosphamide (4-OHCP). Its therapeutic effectiveness is determined by the 4-OHCP concentration. Several analytical methods in plasma
Yahdiana Harahap +3 more
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Heliyon, 2021 Cyclophosphamide is a nitrogen mustard class of drugs that are often used in cancer chemotherapy. However, the use of Cyclophosphamide in high doses over a long period has been shown to increase the risk of developing secondary cancer.
Yahdiana Harahap +4 more
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Proceedings of the Nutrition Society, 2004 The achievement of optimal folate status to prevent neural-tube defects, and possibly other diseases, is hindered by the well-recognised incomplete bioavailability of the natural folates found in foods compared with the synthetic vitamin, folic acid.
Helene, McNulty, Kristina, Pentieva
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Effect of Ginger on Inflammatory Diseases
Molecules, 2022 Ulcerative colitis, Crohn’s disease, rheumatoid arthritis, psoriasis, and lupus erythematosus are some of common inflammatory diseases. These affections are highly disabling and share signals such as inflammatory sequences and immune dysregulation.
Pura Ballester +5 more
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Busulfan bioavailability [PDF]
Blood, 1994 Busulfan is widely used as a component of the myeloablative therapy in bone marrow transplantation. Recent studies have shown that the drug disposition is altered in children and is associated with less therapeutic effectiveness, lower toxicities, and higher rates of engraftment failure.
M, Hassan +8 more
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Carbohydrate bioavailability [PDF]
British Journal of Nutrition, 2005 There is consensus that carbohydrate foods, in the form of fruit, vegetables and whole-grain products, are beneficial to health. However, there are strong indications that highly processed, fibre-depleted, and consequently rapidly digestible, energy-dense carbohydrate food products can lead to over-consumption and obesity-related diseases.
Klaus N, Englyst, Hans N, Englyst
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The Bioavailability of Drugs—The Current State of Knowledge
Molecules, 2023 Drug bioavailability is a crucial aspect of pharmacology, affecting the effectiveness of drug therapy. Understanding how drugs are absorbed, distributed, metabolized, and eliminated in patients’ bodies is essential to ensure proper and safe treatment ...
Marlena Stielow +5 more
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Nanoemulsion: An Emerging Novel Technology for Improving the Bioavailability of Drugs
Scientifica, 2023 The pharmaceutical sector has made considerable strides recently, emphasizing improving drug delivery methods to increase the bioavailability of various drugs. When used as a medication delivery method, nanoemulsions have multiple benefits.
Preeti +9 more
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Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics
Biomedicines, 2022 The low water solubility of pharmacoactive molecules limits their pharmacological potential, but the solubility parameter cannot compromise, and so different approaches are employed to enhance their bioavailability. Pharmaceutically active molecules with
Dixit V. Bhalani +3 more
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Flavonoid Bioavailability and Attempts for Bioavailability Enhancement [PDF]
Nutrients, 2013 Flavonoids are a group of phytochemicals that have shown numerous health effects and have therefore been studied extensively. Of the six common food flavonoid classes, flavonols are distributed ubiquitously among different plant foods whereas appreciable amounts of isoflavones are found in leguminous plant-based foods.
Surangi Thilakarathna, H. Rupasinghe
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