Results 11 to 20 of about 719,874 (416)

The Bioavailability of Drugs—The Current State of Knowledge

Molecules, 2023
Drug bioavailability is a crucial aspect of pharmacology, affecting the effectiveness of drug therapy. Understanding how drugs are absorbed, distributed, metabolized, and eliminated in patients’ bodies is essential to ensure proper and safe treatment ...
Marlena Stielow, Adrianna Witczyńska, Natalia Kubryń, Łukasz Fijałkowski, J. Nowaczyk, A. Nowaczyk   +5 more
semanticscholar   +1 more source

Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics

Biomedicines, 2022
The low water solubility of pharmacoactive molecules limits their pharmacological potential, but the solubility parameter cannot compromise, and so different approaches are employed to enhance their bioavailability. Pharmaceutically active molecules with
Dixit V. Bhalani, Bhingaradiya Nutan, Avinash Kumar, Arvind K. Singh Chandel   +3 more
semanticscholar   +1 more source

Polyphenols and Human Health: The Role of Bioavailability

Nutrients, 2021
Polyphenols are a group of phytochemicals with potential health-promoting effects. They are classified as flavonoid (flavonols, flavanols, flavones, flavanones, isoflavones, and anthocyanins) and non-flavonoid molecules (phenolic acids, hydroxycinnamic ...
Chiara Di Lorenzo, F. Colombo, S. Biella, C. Stockley, P. Restani   +4 more
semanticscholar   +1 more source

Improving Curcumin Bioavailability: Current Strategies and Future Perspectives

Pharmaceutics, 2021
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is also characterized by problematic drug delivery and scarce bioavailability, representing the main problem related to the use of this compound.
Rita Tabanelli, Simone Brogi, V. Calderone   +2 more
semanticscholar   +1 more source

Bioavailability in soils [PDF]

, 2011
The consumption of locally-produced vegetables by humans may be an important exposure pathway for soil contaminants in many urban settings and for agricultural land use.
A Göthberg, A Marin, ACC Plette, AJ Maclean, AL Nolan, AL Nolan, B Buchter, BD Traulsen, BE Davies, BJ Alloway, BS Haslett, BS Shane, C Cobbett, CA Grant, CA Grant, CA Grant, CH Williams, CJ Cappon, CL Luo, CN Geng, CS Hassler, CS Hassler, D Sauerbeck, D Voutsa, DE Salt, DE Salt, DJ Brus, DJ Brus, DJ Brus, DJ Hatch, DM Toro Di, DR Parker, E Brand, E Grill, E Sipter, E Smolders, E Smolders, E Smolders, E Sposito, EA Woolson, EE Cary, EJJ Kalis, F Degryse, F Degryse, F Degryse, F Degryse, F Douay, F Haghiri, FJ Zhao, G Jansson, G Sposito, GA Fleming, GM Thomas, GP Warren, GT Yuran, H Mosbaek, HCH Hahne, IM McKenna, IO Plekhanova, J Ingwersen, JA Ericksen, JC Popelka, JC Tjell, JE Eriksson, JL Hall, JL Hopper, JL Wang, JL Xu, JM Gong, JR Preer, JR Preer, JR Wang, JW Dalenberg, JW Dalenberg, KC Jones, KG Tiller, KR Dunbar, LA Sparrow, LD Tyler, LL Hendrickson, LP Weng, LP Weng, M Helal, M Krauss, M Quaghebeur, M Sobotik, MB McBride, MF Hovmand, MI Mattina, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, ML Adams, MR Farfel, MTF Wong, NA Maier, NA Maier, OK Vatamaniuk, PD Alexander, PFAM Römkens, PJ Florijn, PJ Florijn, PJ Florijn, PJ Florijn, PMC Antunes, PMC Antunes, PR Anderson, Q Xue, R Hough, R Rellan-Alvarez, R Vogeli-Lange, RA Efroymson, RA Khattak, RH Dowdy, RJ Bowell, RJ Reid, RJM Hudson, RL Chaney, RL Chaney, RL Chaney, RL Hough, RL Hough, RM Harrison, RN Collins, RN Reese, RP Narwal, RT Checkai, S Clemens, S Goldberg, S Goldberg, S Sauvé, S Sauvé, S Tandy, S Tandy, S Thakali, SA Barber, SDW Comber, SE Lorenz, SL Brown, SL McGowen, SN Adams, SN Whiting, SP McGrath, T Adhikari, T Cheng, T Kuboi, T Sterckeman, TL Creger, V Page, W Peijnenburg, W Vries de, W Vries de, WJ Garcia, WP Chen, X Cao, X Du, XP Wang, Y Guo, Y Nakamaru, YT Guo   +164 more
core   +2 more sources

Polyphenols: food sources and bioavailability.

American Journal of Clinical Nutrition, 2004
Polyphenols are abundant micronutrients in our diet, and evidence for their role in the prevention of degenerative diseases such as cancer and cardiovascular diseases is emerging.
C. Manach, A. Scalbert, C. Morand, C. Rémésy, L. Jiménez   +4 more
semanticscholar   +1 more source

State of the Art of Anthocyanins: Antioxidant Activity, Sources, Bioavailability, and Therapeutic Effect in Human Health

Antioxidants, 2020
The antioxidant activity of anthocyanins in food is well known. Numerous antioxidant assays have been proposed to measure the capacity of anthocyanins to prevent the oxidation process that naturally occurs. Different solvents, temperatures, and pH levels
Noelia Tena, Julia Martín, A. Asuero
semanticscholar   +1 more source

Hepcidin and iron homeostasis during pregnancy. [PDF]

, 2014
Hepcidin is the master regulator of systemic iron bioavailability in humans. This review examines primary research articles that assessed hepcidin during pregnancy and postpartum and report its relationship to maternal and infant iron status and birth ...
Cadwell, Brooke, Day, Jessica, Koenig, Mary Dawn, Nemeth, Elizabeta, Tussing-Humphreys, Lisa   +4 more
core   +1 more source

Validated Reversed-Phase Liquid Chromatographic Method with Gradient Elution for Simultaneous Determination of the Antiviral Agents: Sofosbuvir, Ledipasvir, Daclatasvir, and Simeprevir in Their Dosage Forms

Molecules, 2020
A simple, rapid, sensitive, and precise reversed-phase liquid chromatographic method was developed and validated for the simultaneous determination of four direct-acting antivirals, sofosbuvir (SF), ledipasvir (LD), declatasvir (DC), and simeprevir (SM),
Essam Ezzeldin, Nisreen F. Abo-Talib, Marwa H. Tammam, Yousif A. Asiri, Abd El-Galil E. Amr, Abdulrahman A. Almehizia   +5 more
doaj   +1 more source

Bioavailability of orange juice (poly)phenols: the impact of short-term cessation of training by male endurance athletes [PDF]

, 2017
Background: Physical exercise has been reported to increase the bioavailability of citrus flavanones. Objective: To investigate the bioavailability of orange juice (OJ) (poly)phenols in endurance-trained men before and after cessation of training for 7 ...
Crozier, Alan, Garcia, Ada L., Ludwig, Iziar A., Malkova, Dalia, Moreno-Rojas, Manuel, Natase, Ana-Maria, Pereira-Caro, Gema, Polyviou, Thelma   +7 more
core   +2 more sources