Results 11 to 20 of about 766,095 (388)

The Bioavailability of Drugs—The Current State of Knowledge

open access: yesMolecules, 2023
Drug bioavailability is a crucial aspect of pharmacology, affecting the effectiveness of drug therapy. Understanding how drugs are absorbed, distributed, metabolized, and eliminated in patients’ bodies is essential to ensure proper and safe treatment ...
Marlena Stielow   +5 more
semanticscholar   +1 more source

Flavonoid Bioavailability and Attempts for Bioavailability Enhancement [PDF]

open access: yesNutrients, 2013
Flavonoids are a group of phytochemicals that have shown numerous health effects and have therefore been studied extensively. Of the six common food flavonoid classes, flavonols are distributed ubiquitously among different plant foods whereas appreciable amounts of isoflavones are found in leguminous plant-based foods.
Surangi Thilakarathna, H. Rupasinghe
openaire   +3 more sources

Cyclodextrin Inclusion Complexes for Improved Drug Bioavailability and Activity: Synthetic and Analytical Aspects

open access: yesPharmaceutics, 2023
Many active pharmaceutical ingredients show low oral bioavailability due to factors such as poor solubility and physical and chemical instability.
Álvaro Sarabia-Vallejo   +4 more
semanticscholar   +1 more source

Folate Bioavailability [PDF]

open access: yesProceedings of the Nutrition Society, 2004
The achievement of optimal folate status to prevent neural-tube defects, and possibly other diseases, is hindered by the well-recognised incomplete bioavailability of the natural folates found in foods compared with the synthetic vitamin, folic acid.
Helene, McNulty, Kristina, Pentieva
openaire   +2 more sources

Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics

open access: yesBiomedicines, 2022
The low water solubility of pharmacoactive molecules limits their pharmacological potential, but the solubility parameter cannot compromise, and so different approaches are employed to enhance their bioavailability. Pharmaceutically active molecules with
Dixit V. Bhalani   +3 more
semanticscholar   +1 more source

Polyphenols and Human Health: The Role of Bioavailability

open access: yesNutrients, 2021
Polyphenols are a group of phytochemicals with potential health-promoting effects. They are classified as flavonoid (flavonols, flavanols, flavones, flavanones, isoflavones, and anthocyanins) and non-flavonoid molecules (phenolic acids, hydroxycinnamic ...
Chiara Di Lorenzo   +4 more
semanticscholar   +1 more source

Bioavailability enhancement

open access: yesWorld Journal of Advanced Research and Reviews, 2023
The rate and extent (amount) of unmodified medication absorption from its dose form is referred to as bioavailability. It is one of the critical criteria for achieving optimal medication concentration in the systemic circulation. Bioavailability is a significant factor of a drug's therapeutic efficacy, which is determined by the drug's solubility in ...
Vaishnavi Tejram Gabhane   +5 more
openaire   +1 more source

Bioavailability of diphenylhydantoin [PDF]

open access: yesClinical Pharmacology & Therapeutics, 1974
A four‐way crossover study was performed in 8 adult volunteers using a Latin square design with 4 groups of 2 subiects arranged in order of increasing body weight. Single 100 mg doses of diphenylhydantoin (DPH) sodium were administered as an aqueous solution (treatment A), the innovator's capsule (treatment B), alld a commercially available generic ...
Albert, Kenneth S.   +4 more
openaire   +4 more sources

Bioavailability of Hesperidin and Its Aglycone Hesperetin—Compounds Found in Citrus Fruits as a Parameter Conditioning the Pro-Health Potential (Neuroprotective and Antidiabetic Activity)—Mini-Review

open access: yesNutrients, 2022
Hesperidin and hesperetin are polyphenols that can be found predominantly in citrus fruits. They possess a variety of pharmacological properties such as neuroprotective and antidiabetic activity. However, the bioavailability of these compounds is limited
Kamil Wdowiak   +4 more
semanticscholar   +1 more source

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