Results 71 to 80 of about 469,546 (342)

UPLC–MS/MS assay for quantification of an inhibitor of kinases (Foretinib) in plasma: Application to a pharmacokinetic study in rats

open access: yesSaudi Pharmaceutical Journal, 2020
Foretinib, an oral multikinase inhibitor, is known to have anti-tumor effects against cancers. The doses and the levels of foretinib vary based on the type of cancer to be treated.
Essam Ezzeldin   +4 more
doaj  

Stream order and connectivity affect phosphorus distribution in plain river network

open access: yesEnvironmental Pollutants & Bioavailability, 2020
The order and connectivity of streams influence phosphorus distribution extensively. In this work, the space-and-time variabilities of total phosphorus (TP), particulate phosphorus (PP), total dissolved phosphorus (TDP), dissolved reactive phosphorus ...
Huihua Lyu, Feng Zhou, Na Li
doaj   +1 more source

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

open access: yesAdvanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi   +11 more
wiley   +1 more source

Evaluating the invasive plant, Prosopis juliflora in the two initial growth stages as a potential candidate for heavy metal phytostabilization in metalliferous soil

open access: yesEnvironmental Pollutants & Bioavailability, 2019
Anthropogenic activities leads to increase in toxic metals in the environment. The toxicity of Cd, Cr and Pb to P. juliflora were tested in agar media; Seeds germinated in 25, 50 and 100 mg/L Pb; 5, 10 and 20 mg/ 10 L Cd; and 10 mg/L Cr were mostly ...
Kamal Usman   +2 more
doaj   +1 more source

Enhanced biodegradation of m-dichlorobenzene by Brevibacillus agri under the coexistence system of Zn(II) and Se(IV)

open access: yesEnvironmental Pollutants & Bioavailability, 2020
Appropriate concentration of biological growth additives can improve the treatment effect of organic waste gas by microorganisms. In this work, the growth capability of Brevibacillus agri and the biodegradation efficiency of m-dichlorobenzene were ...
Bairen Yang   +6 more
doaj   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao   +8 more
wiley   +1 more source

Soybean protein hydrolysate-formaldehyde-urea block copolymer for controlled release fertilizer

open access: yesEnvironmental Pollutants & Bioavailability, 2019
Urea formaldehyde (UF) was modified by the soybean protein hydrolysate (SPH) to adjust the rate of nitrogen, phosphorus, and potassium (NPK) release. The SPH section can copolymerize into the UF molecules.
Na Liu   +3 more
doaj   +1 more source

Biodegradation of o-dichlorobenzene by Bacillus cereus DL-1:kinetics, degradation pathway, biodegradability and performance in biotrickling filter

open access: yesEnvironmental Pollutants & Bioavailability, 2020
o -Dichlorobenzene could be mineralized as the sole carbon and energy source by Bacillus cereus DL-1. In this work, Haldane–Andrews and pseudo-first-order models were used to simulate the growth and degradation abilities of the strain.
Bairen Yang   +4 more
doaj   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

open access: yesAdvanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song   +8 more
wiley   +1 more source

Efficient adsorptive removal of Congo red from aqueous solution by synthesized zeolitic imidazolate framework-8

open access: yesChemical Speciation & Bioavailability, 2016
Dyes exposure in aquatic environment creates risks to human health and biota due to their intrinsic toxic mutagenic and carcinogenic characteristics.
Canlan Jiang   +3 more
doaj   +1 more source

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