Results 171 to 180 of about 99,905 (246)

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Linking cortical structure and delirium in the elderly: insights from cohort study and shared genetic risk analysis. [PDF]

J Transl Med
Chen Y, Zheng J, Shen R, Cheng J, Wang X, Liang T, Sun Y, Wu J, Zheng Z, Zhou T, Li J, Liu W, Li Y, Zeng G, Song W.   +14 more
europepmc   +1 more source

When Rare Is Not Small: Amyotrophic Lateral Sclerosis Initiatives and Therapy

Exploration, EarlyView.
In the precision‐medicine era, rare diseases must not be sidelined in translational infrastructure. The Mr. Cai Lei—led “Ice‐Breaking Team” turns an amyotrophic lateral sclerosis patient community into a sustainable ecosystem, realigning philanthropy, data, and research and development to reshape rare‐disease pipelines and guide precision therapies ...
Yang Liu, Xue Xia, Yingfang Chen, Haoying Yang, Xiaochen Chen, Lei Cai, Bingyang Shi   +6 more
wiley   +1 more source

Biobanks need pharma [PDF]

Nature, 2009
openaire   +2 more sources

A UK Biobank Study on Genetic Variants in Pattern-Recognition Receptor (PRR) Signaling Indicates Self-Perpetuatin Inflammation of Cholesteatoma. [PDF]

J Pers Med
Almomani M, Vlastos I, Gkouskou K, Drimalas N, Hajiioannou J.   +4 more
europepmc   +1 more source

A Research Classification for Long COVID: Symptom Frequency and Severity Improve Accuracy of Machine Learning Models

Chronic Diseases and Translational Medicine, EarlyView.
Leonard A. Jason, Lauren Ruesink, Jacob Furst, Ben Z. Katz   +3 more
wiley   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

The Prime Diet Quality Score (PDQS), chronic disease and cause-specific mortality in UK Biobank: a prospective study. [PDF]

Eur J Nutr
Kronsteiner-Gicevic S, Thompson AS, Cordova R, Gaggl M, Woodside JV, Cassidy A, Rohrmann S, Kühn T.   +7 more
europepmc   +1 more source

Genetic risk factors for pneumonia differ by patient subgroup. [PDF]

EBioMedicine
Heikkilä A, Sliz E, Väyrynen S, Reis K, Elnahas AG, Reigo A, Esko T, FinnGen, Estonian Biobank Research Team, Kettunen J, Hautala T.   +10 more
europepmc   +1 more source

Fine-mapping a genome-wide meta-analysis of 98,374 migraine cases identifies 181 sets of candidate causal variants. [PDF]

Nat Commun
Hautakangas H, Kartau J, FinnGen, Palotie A, Pirinen M, International Headache Genetics Consortium.   +5 more
europepmc   +1 more source