Results 51 to 60 of about 3,236,821 (283)

Carbon dioxide and trace oxygen concentrations impact growth and product formation of the gut bacterium Phocaeicola vulgatus

BMC Microbiology, 2023
Background The promising yet barely investigated anaerobic species Phocaeicola vulgatus (formerly Bacteroides vulgatus) plays a vital role for human gut health and effectively produces organic acids.
Laura Keitel, Kristina Braun, Maurice Finger, Udo Kosfeld, Stanislav Yordanov, Jochen Büchs   +5 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hyperspectral Imaging Techniques for Lyophilization: Advances in Data‐Driven Modeling Strategies and Applications

Advanced Science
Lyophilization, aka freeze drying, is a key process used in the production of biotherapeutic products. The optimization of lyophilization formulations and operations is a slow process that could be accelerated by on‐line analytics.
Huiwen Yu, Prakitr Srisuma, Cedric Devos, Jie Wang, Allan S. Myerson, Richard D. Braatz   +5 more
doaj   +1 more source

Tailoring tumor-recognizable hyaluronic acid–lipid conjugates to enhance anticancer efficacies of surface-engineered natural killer cells

Nano Convergence, 2023
Natural killer (NK) cells have clinical advantages in adoptive cell therapy owing to their inherent anticancer efficacy and their ability to identify and eliminate malignant tumors. However, insufficient cancer-targeting ligands on NK cell surfaces often
Chae Eun Lee, Sungjun Kim, Hee Won Park, Wonjeong Lee, Ashok Kumar Jangid, Yonghyun Choi, Woo-Jin Jeong, Kyobum Kim   +7 more
doaj   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Routes to industrial scalability to maximise investment in engineering biology in the UK—A bioplastics small and medium‐sized enterprise perspective

Engineering Biology
Focus on engineering biology is at the forefront of the UK government's objectives, being one of their five critical technologies (the others being quantum technologies, artifical intelligence, semiconductors, and future telecommunications), with a ...
Amy Switzer, Laima Šusta, Paul Mines
doaj   +1 more source

Phytoremediation of Cadmium: Physiological, Biochemical, and Molecular Mechanisms

Biology, 2020
Cadmium (Cd) is one of the most toxic metals in the environment, and has noxious effects on plant growth and production. Cd-accumulating plants showed reduced growth and productivity.
A. Raza, Madiha Habib, Shiva Najafi Kakavand, Zainab Zahid, N. Zahra, R. Sharif, M. Hasanuzzaman   +6 more
semanticscholar   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Development of predictive model for the fixed-bed column reactor

Applied Water Science, 2023
The present study aims at development of a mathematical model for the fixed-bed column adsorption that relates the reactor parameters with the breakthrough curve. Effects of operating parameters like bed height, flow rate, initial adsorbate concentration
Jyoti Singh, Santhosh Kumar Kumaresan, Sarvanshi Swaroop, Vishal Mishra   +3 more
doaj   +1 more source