Results 51 to 60 of about 579,757 (320)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Chinese herbal Jin-Ying-Tang attenuates the inflammatory response by inhibiting the activation of TLR4/MyD88/TRAF-6/NIK pathway at the mRNA level in LPS-stimulated mouse mammary epithelial cells

Journal of Veterinary Research, 2016
Introduction: The effects of Jin-Ying-Tang (JYT) on Toll-like Receptor 4 (TLR4) signalling transduction of lipopolysaccharide (LPS)-stimulated mouse mammary epithelial cells (MECs) in vitro were examined.
Yi Qiong, Li Xin, Li Yuan-Fang, Yang Hang, Zhang Xiao-Yi, Ma Zhe, Wang Lu   +6 more
doaj   +1 more source

Application of the Zimm-Bragg Model to the Removal of Azo Dyes with Pectin

Adsorption Science & Technology, 2021
In this work, the ability of pectin (Pec) to remove direct red 80 (DR80), Congo red (CR), methyl orange (MO), and methyl red (MR) was studied. The removal percentages under adequate pH and ionic strength conditions were as follows: DR80 (99.5%), CR (99.8%
Juan Antonio Lozano-Álvarez, Juan Jáuregui-Rincón, Iliana E. Medina-Ramírez, Rogelio Salinas-Gutiérrez, Jorge Martín Alférez Chávez, Guadalupe Javier Araiza-Arvilla   +5 more
doaj   +1 more source

A structured approach for the engineering of biochemical network models, illustrated for signalling pathways [PDF]

, 2008
http://dx.doi.org/10.1093/bib/bbn026Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology.
Alves, Breitling, Brown, D. Gilbert, Fisher, Huang, Hucka, Kholodenko, Kholodenko, Kolch, Levchenko, M. Heiner, Mendes, Orton, R. Breitling, R. Orton, Schoeberl, Wiley   +17 more
core   +4 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Glucose limited feed strategy leads to increased production of fusicocca-2,10(14)-diene by Saccharomyces cerevisiae

AMB Express, 2018
Fusicocca-2,10(14)-diene (FCdiene) is a diterpene which is interesting as a precursor of the anti-cancer drug fusicoccin A and therefore for pharmaceutical applications. Production of FCdiene using a genetically modified Saccharomyces cerevisiae has been
Lisa Marie Halka, Christian Nowacki, Alica Kleinschmidt, Kevin Koenen, Rolf Wichmann   +4 more
doaj   +1 more source

Stochastic neural network models for gene regulatory networks [PDF]

, 2003
Recent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of genome dynamics by means of mathematical modelling.
Burrage, K., Tian, T.
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Routes to industrial scalability to maximise investment in engineering biology in the UK—A bioplastics small and medium‐sized enterprise perspective

Engineering Biology
Focus on engineering biology is at the forefront of the UK government's objectives, being one of their five critical technologies (the others being quantum technologies, artifical intelligence, semiconductors, and future telecommunications), with a ...
Amy Switzer, Laima Šusta, Paul Mines
doaj   +1 more source

Black glucose-releasing silicon elastomer rings for fed-batch operation allow measurement of the oxygen transfer rate from the top and optical signals from the bottom for each well of a microtiter plate

BMC Biotechnology, 2023
Background In industrial microbial biotechnology, fed-batch processes are frequently used to avoid undesirable biological phenomena, such as substrate inhibition or overflow metabolism.
Sarah Sparviero, Laura Barth, Timm Keil, Carl Dinter, Christoph Berg, Clemens Lattermann, Jochen Büchs   +6 more
doaj   +1 more source