Results 51 to 60 of about 3,092,070 (229)

Rational Enzyme Engineering Through Biophysical and Biochemical Modeling

, 2016
Due to its importance in the pharmaceutical industry, ligand dynamic simulations have experienced a great expansion. Using all-atom models and cutting-edge hardware, one can perform nonbiased ligand migration, active site search, and binding studies.
Sandra Acebes, Elena Fernández-Fueyo, Emanuele Monza, M. Lucas, David Almendral, F. J. Ruiz-Dueñas, H. Lund, Ángel T. Martínez, V. Guallar   +8 more
semanticscholar   +1 more source

Routes to industrial scalability to maximise investment in engineering biology in the UK—A bioplastics small and medium‐sized enterprise perspective

Engineering Biology
Focus on engineering biology is at the forefront of the UK government's objectives, being one of their five critical technologies (the others being quantum technologies, artifical intelligence, semiconductors, and future telecommunications), with a ...
Amy Switzer, Laima Šusta, Paul Mines
doaj   +1 more source

Phytoremediation of Cadmium: Physiological, Biochemical, and Molecular Mechanisms

Biology, 2020
Cadmium (Cd) is one of the most toxic metals in the environment, and has noxious effects on plant growth and production. Cd-accumulating plants showed reduced growth and productivity.
A. Raza, Madiha Habib, Shiva Najafi Kakavand, Zainab Zahid, N. Zahra, R. Sharif, M. Hasanuzzaman   +6 more
semanticscholar   +1 more source

Serum-free lentiviral vector production is compatible with medium-resident nuclease activity arising from adherent HEK293T host cells engineered with a nuclease-encoding transgene

Heliyon, 2023
At present lentiviral vector production for cell and gene therapy commonly involves transient plasmid transfection of mammalian cells cultivated in serum-containing media and addition of exogenous nuclease to reduce host cell and plasmid DNA impurities ...
Sadfer Ali, Milena Rivera, John Ward, Eli Keshavarz-Moore, Chris Mason, Darren N. Nesbeth   +5 more
doaj  

The Soluble and Particulate Form of Alginates Positively Regulate Immune Response [PDF]

Iranian Journal of Immunology, 2018
Background: Alginate materials have been widely employed for biomedical applications ranging from wound healing to cancer treatment. However, how alginate materials affect the immune system is largely unknown. Objective: To explore the impact of alginate
Fei Ge, Longbao Zhu, Liangjun Yang, Wanzhen Li, Shenghua Wei, Yugui Tao, Guocheng Du   +6 more
doaj   +1 more source

Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production

Metabolites, 2015
Engineering cyanobacteria into photosynthetic microbial cell factories for the production of biochemicals and biofuels is a promising approach toward sustainability.
M. C. Lai, Ethan I. Lan
semanticscholar   +1 more source

Modular systems metabolic engineering enables balancing of relevant pathways for l-histidine production with Corynebacterium glutamicum

Biotechnology for Biofuels, 2019
Background l-Histidine biosynthesis is embedded in an intertwined metabolic network which renders microbial overproduction of this amino acid challenging. This is reflected in the few available examples of histidine producers in literature.
Andreas Schwentner, André Feith, Eugenia Münch, Judith Stiefelmaier, Ira Lauer, Lorenzo Favilli, Christoph Massner, Johannes Öhrlein, Bastian Grund, Andrea Hüser, Ralf Takors, Bastian Blombach   +11 more
doaj   +1 more source

An overview on biofuel and biochemical production by photosynthetic microorganisms with understanding of the metabolism and by metabolic engineering together with efficient cultivation and downstream processing

Bioresources and Bioprocessing, 2015
Biofuel and biochemical production by photosynthetic microorganisms such as cyanobacteria and algae is attractive to improve energy security and to reduce CO2 emission, contributing to the environmental problems such as global warming.
Dayanidhi Sarkar, K. Shimizu
semanticscholar   +1 more source

Customized microscale approach for optimizing two-phase bio-oxidations of alkanes with high reproducibility

Microbial Cell Factories, 2017
Background Numerous challenges remain to achieve industrially competitive space–time yields for bio-oxidations. The ability to rapidly screen bioconversion reactions for characterization and optimization is of major importance in bioprocess development ...
Johannes F. Kolmar, Oliver Thum, Frank Baganz   +2 more
doaj   +1 more source

Editorial: Biochemical and genetic tools to investigate the underlying mechanisms and treatment of sensorimotor pathologies

Frontiers in Molecular Neuroscience, 2022
Thomas Haynes Hutson, Arnau Hervera, Arnau Hervera, Arnau Hervera, Arnau Hervera   +4 more
doaj   +1 more source