Results 71 to 80 of about 579,757 (320)

Carbon dioxide and trace oxygen concentrations impact growth and product formation of the gut bacterium Phocaeicola vulgatus

BMC Microbiology, 2023
Background The promising yet barely investigated anaerobic species Phocaeicola vulgatus (formerly Bacteroides vulgatus) plays a vital role for human gut health and effectively produces organic acids.
Laura Keitel, Kristina Braun, Maurice Finger, Udo Kosfeld, Stanislav Yordanov, Jochen Büchs   +5 more
doaj   +1 more source

システム生物学のための統合解析シミュレータ WinBEST-KIT の開発 [PDF]

, 2018
Previously, I developed the biochemical reaction simulator called WinBEST-KIT (Biochemical Engineering System analyzing Tool-KIT, which runs under Microsoft Windows) for analyzing complicated biochemical reaction systems such as metabolic pathways ...
Sekiguchi, Tatsuya, セキグチ, タツヤ, 関口, 達也   +2 more
core  

Recent advances in 3D printing of biomaterials. [PDF]

, 2015
3D Printing promises to produce complex biomedical devices according to computer design using patient-specific anatomical data. Since its initial use as pre-surgical visualization models and tooling molds, 3D Printing has slowly evolved to create one-of ...
Chia, Helena N, Wu, Benjamin M
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

An SFN-YOLO-based detection method for the fermentation stage in the anaerobic digestion process

iScience
Summary: Anaerobic digestion is an effective and low-carbon approach for biomass utilization and energy recovery. To accurately determine fermentation stages and enhance process control, this paper proposes an anaerobic digestion fermentation stage ...
Peng Liu, Shengxian Cao, Gong Wang, Siyuan Fan, Tianyi Sun, An Yan   +5 more
doaj   +1 more source

Benchmarking biopharmaceutical process development and manufacturing cost contributions to R&D

mAbs, 2020
This study aims to benchmark and analyze the process development and manufacturing costs across the biopharmaceutical drug development cycle and their contribution to overall research and development (R&D) costs.
Suzanne S. Farid, Max Baron, Christos Stamatis, Wenhao Nie, Jon Coffman   +4 more
doaj   +1 more source

Controlled diffusion processes with markovian switchings for modeling dynamical engineering systems [PDF]

, 2009
A modeling approach to treat noisy engineering systems is presented. We deal with controlled systems that evolve in a continuous-time over finite time intervals, but also in continuous interaction with environments of intrinsic variability. We face the
Cañada, Héctor, Romera, Rosario
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Automation on the generation of genome scale metabolic models [PDF]

, 2012
Background: Nowadays, the reconstruction of genome scale metabolic models is a non-automatized and interactive process based on decision taking. This lengthy process usually requires a full year of one person's work in order to satisfactory collect ...
de Córdoba, P. Fernández, Fuente, D., Gamermann, D., Montagud, A., Reyes, R., Triana, J., Urchuegía, J. F.   +6 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source