Results 91 to 100 of about 143,906 (309)
, 2020 This course examines the molecular events in cell function using molecular genetics, cell biology, and fundamental biochemistry; using both prokaryotic and eukaryotic systems. The laboratory will emphasize fundamental techniques used in molecular biology.
North Carolina Agricultural and Technical State University
core
Teneurins in development and disease [PDF]
, 2008 The teneurins are a novel type II transmembrane protein family originally discovered in Drosophila and highly conserved between invertebrates and vertebrates.
Kenzelmann Broz, Daniela
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
, 2017 This article is published on Elephant in the lab – a blog journal on science policy. It is part of a series of articles analysing the authorship performance in 27 scientific subject areas.
Schmidt, Martin +2 more
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Insights from the neural guidance factor Netrin-1 into neurodegeneration and other diseases
Frontiers in Molecular NeuroscienceNetrin-1 was initially discovered as a neuronal growth cue for axonal guidance, and its functions have later been identified in inflammation, tumorigenesis, neurodegeneration, and other disorders. We have recently found its alterations in the brains with
Minqi Cai +5 more
doaj +1 more source
The Spetses Summer Schools on Molecular and Developmental Biology [PDF]
, 2013 The Spetses Summer Schools - A Tribute to Marianne Grunberg-Manago - Founding and More than 40 Years of the School - How Spetses Summer Schools Were Run - Financing the Spetses Summer Schools - Past and Future of the Spetses Summer Schools - List
Feldmann, Horst
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Investigating the antineoplastic effects of the synthetic retinoid ST1926 and its underlying molecular mechanism on prostate cancer - [PDF]
, 2015 Thesis. M.Sc. American University of Beirut. Department of Biochemistry and Molecular Genetics 2015. W 4 S189i 2015Advisor: Dr. Nadine Darwiche, Professor, Department of Biochemistry and Molecular Genetics ; Dr.
Samman, Houda Hassan
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source