Results 31 to 40 of about 360,147 (291)

Integration of CRISPR/Cas9 with artificial intelligence for improved cancer therapeutics

Journal of Translational Medicine, 2022
Gene editing has great potential in treating diseases caused by well-characterized molecular alterations. The introduction of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9)–based gene-editing tools ...
Ajaz A. Bhat, Sabah Nisar, Soumi Mukherjee, Nirmalya Saha, Nageswari Yarravarapu, Saife N. Lone, Tariq Masoodi, Ravi Chauhan, Selma Maacha, Puneet Bagga, Punita Dhawan, Ammira Al-Shabeeb Akil, Wael El-Rifai, Shahab Uddin, Ravinder Reddy, Mayank Singh, Muzafar A. Macha, Mohammad Haris   +17 more
doaj   +1 more source

COVID-19 associated coagulopathy: A bibliometric investigation

Heliyon, 2023
Infection with SARS-CoV-2 initiates an immune-hemostatic response. While both systems are intimately connected and necessary for an efficient immune response to contain the infection, excessive coagulation activation might exceed the valuable benefits by
Nahla A. Alshaikh
doaj   +1 more source

Identification, Genome Sequencing, and Characterizations of Helicobacter pylori Sourced from Pakistan

Microorganisms, 2023
The stomach’s colonization by Helicobacter pylori (H. pylori) results in gastritis, ulcers, and stomach cancer. Frequently, pain is treated with medication, but resistant H. pylori infections are not.
Anees Fatima, Muhammad Ibrahim, Adil Naseer, Arshid Pervez, Muhammad Asad, Aamer Ali Shah, Fariha Hasan, Wadi B. Alonazi, Ifra Ferheen, Samiullah Khan   +9 more
doaj   +1 more source

Regulation of tomato fruit ripening [PDF]

, 2009
Fruit ripening is a sophisticatedly orchestrated developmental process, unique to plants, that results in major physiological and metabolic changes, ultimately leading to fruit decay and seed dispersal.
Bouzayen, Mondher, Latché, Alain, Pech, Jean-Claude, Pirrello, Julien, Regad, Farid   +4 more
core   +2 more sources

LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis. [PDF]

, 2014
Transcriptional elongation by RNA polymerase (Pol) II is essential for gene expression during cell growth and differentiation. The positive transcription elongation factor b (P-TEFb) stimulates transcriptional elongation by phosphorylating Pol II and ...
Ji, Xiaodan, Lu, Huasong, Luo, Kunxin, Zhou, Qiang   +3 more
core   +2 more sources

Towards Developmental Models of Psychiatric Disorders in Zebrafish

Frontiers in Neural Circuits, 2013
Psychiatric disorders are a diverse set of diseases that affect all aspects of mental function including social interaction, thinking, feeling and mood.
William Howard James Norton
doaj   +1 more source

CAR-T-Cell Therapy in Multiple Myeloma: B-Cell Maturation Antigen (BCMA) and Beyond

Vaccines, 2023
Significant progress has been achieved in the realm of therapeutic interventions for multiple myeloma (MM), leading to transformative shifts in its clinical management.
Abhinava K. Mishra, Ashna Gupta, Gunjan Dagar, Dayasagar Das, Abhijit Chakraborty, Shabirul Haque, Chandra Prakash Prasad, Archana Singh, Ajaz A. Bhat, Muzafar A. Macha, Moez Benali, Kamal S. Saini, Rebecca Ann Previs, Deepak Saini, Dwaipayan Saha, Preyangsee Dutta, Aseem Rai Bhatnagar, Mrinalini Darswal, Abhishek Shankar, Mayank Singh   +19 more
doaj   +1 more source

Biochemistry of Corona Virus: An Overveiw

Asian Journal of Biochemistry Genetics and Molecular Biology, 2022
Coronaviruses forma large family of respiratory viruses having positive (+ve)-stranded RNA (C0V).  Their names are derived from the crown-like shape that is present on their them (surface).
N. J. Caleb, V. Nwankwo, Nweke Celestine Chimaobi, Ugoaghalam Uche James, Uchenna Sampson Igwe, A. Chinedu   +5 more
semanticscholar   +1 more source

BOOL-AN: A method for comparative sequence analysis and phylogenetic reconstruction [PDF]

, 2009
A novel discrete mathematical approach is proposed as an additional tool for molecular systematics which does not require prior statistical assumptions concerning the evolutionary process.
Ari, Eszter, Horváth, Arnold, Ittzés, Péter, Jakó, Éena, Podani, János   +4 more
core   +1 more source

T2D-Db: An integrated platform to study the molecular basis of Type 2 diabetes

BMC Genomics, 2008
Background Type 2 Diabetes Mellitus (T2DM) is a non insulin dependent, complex trait disease that develops due to genetic predisposition and environmental factors.
Sriram S, Lakshmi S Sai, Udayakumar K, Nathan Prasanthi, Dimitrova Nevenka, Agrawal Shipra, Manjusha N, Sengupta Urmi   +7 more
doaj   +1 more source