Results 81 to 90 of about 368,095 (294)
BMC Genomics, 2008 Background Studying mitochondrial (mt) genomics has important implications for various fundamental areas, including mt biochemistry, physiology and molecular biology.
Wu Xiang-Yun +4 more
doaj +1 more source
, 2016 Reduction and reductionism have been central philosophical topics in analytic philosophy of science for more than six decades. Together they encompass a diversity of issues from metaphysics and epistemology.
Hüttemann, Andreas, Love, Alan
core
LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis. [PDF]
, 2014 Transcriptional elongation by RNA polymerase (Pol) II is essential for gene expression during cell growth and differentiation. The positive transcription elongation factor b (P-TEFb) stimulates transcriptional elongation by phosphorylating Pol II and ...
Ji, Xiaodan +3 more
core +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2019 Chromosomal aneuploidy is a defining feature of epithelial cancers. The pattern of aneuploidies is cancer-type specific. For instance, the gain of chromosome 13 occurs almost exclusively in colorectal cancer.
Darawalee Wangsa +16 more
doaj +1 more source
A tale of three kingdoms: Members of the Phylum Nematoda independently acquired the detoxifying enzyme cyanase through horizontal gene transfer from plants and bacteria [PDF]
, 2018 Horizontal gene transfer (HGT) has played an important role in the evolution of nematodes. Among candidate genes, cyanase, which is typically found only in plants, bacteria and fungi, is present in more than 35 members of the Phylum Nematoda, but absent ...
Hoberg, E. P +5 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Bibliometric analysis of publication trends on ocular hygiene and infections in the past two decades
GMS Hygiene and Infection ControlBackground: Ocular hygiene encompasses a spectrum of measures to initiate and maintain adequate ocular cleanliness to prevent eye infections and their further transmission.
Ali, Mohsan +5 more
doaj +1 more source
Worldwide Research Trends on Wheat and Barley: A Bibliometric Comparative Analysis [PDF]
, 2019 Grain cereals such as wheat, barley, rice, and maize are the nutritional basis of humans and animals worldwide. Thus, these crop plants are essential in terms of global food security.
Benavente Barzana, María Elena +3 more
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Quantifying the Diaspora of Knowledge in the Last Century [PDF]
, 2016 Academic research is driven by several factors causing different disciplines to act as "sources" or "sinks" of knowledge. However, how the flow of authors' research interests -- a proxy of human knowledge -- evolved across time is still poorly understood.
Arenas, Alex +2 more
core +2 more sources