Results 91 to 100 of about 2,254,748 (322)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Using augmented reality in molecular case studies to enhance biomolecular structure-function explorations in undergraduate classrooms

open access: yesJournal of Microbiology & Biology Education
Molecular case studies (MCSs) are open educational resources that use a storytelling approach to engage students in biomolecular structure-function explorations, at the interface of biology and chemistry.
Didem Vardar-Ulu   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Lipid-Based Catalysis Demonstrated by Bilayer-Enabled Ester Hydrolysis

open access: yesMembranes
Lipids have not traditionally been considered likely candidates for catalyzing reactions in biological systems. However, there is significant evidence that aggregates of amphiphilic compounds are capable of catalyzing reactions in synthetic organic ...
Shu Liu   +5 more
doaj   +1 more source

Introducing Toxicology into the Biochemistry Curricula: Using Cytochrome c (Cytc) Functionalities as a Model [PDF]

open access: yes, 2013
The electron transport chain (ETC) is a keystone topic of all biochemistry courses at the undergraduate level. Many ETC components, especially cytochrome c (Cytc), are also important to the field of toxicology. Unfortunately, many primarily undergraduate
Borland, Michael
core  

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

Assessing the stability of uncentrifuged serum and plasma analytes at various post-collection intervals

open access: yesJournal of Laboratory Medicine
Our study aimed to assess the stability of 26 biochemistry analytes in serum or plasma samples separated from blood samples centrifuged at different time intervals after collection, simulating sample transport via despatch delivery systems.
Mokhsin Atiqah   +10 more
doaj   +1 more source

Flipping Veterinary Biochemistry, Anatomy, and Physiology: Students’ Engagement and Perception

open access: yesVeterinary Sciences
Flipped classroom (FC) is a teaching method where traditional learning roles are inverted. Students are provided with material in advance and are expected to study the content prior to in-class sessions.
Christelle de Brito, José Terrado
doaj   +1 more source

Studies in the biochemistry of micro-organisms [PDF]

open access: green, 1932
Percival Walter Clutterbuck   +3 more
openalex   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

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