Results 151 to 160 of about 1,003,439 (343)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Biochemistry and Cell Biology of Ageing: Part V, Anti-Ageing Interventions [PDF]

Korolchuk, Viktor I., Harris, J. Robin
openalex   +1 more source

Biochemistry, Cell Biology, and Pathophysiology of the Innate Immune cGAS–cGAMP–STING Pathway [PDF]

, 2022
Christopher Ritchie, Jacqueline A. Carozza, Lingyin Li   +2 more
openalex   +1 more source

PHLPP1 counter-regulates STAT1-mediated inflammatory signaling. [PDF]

, 2019
Inflammation is an essential aspect of innate immunity but also contributes to diverse human diseases. Although much is known about the kinases that control inflammatory signaling, less is known about the opposing phosphatases.
Cohen Katsenelson, Ksenya, Glass, Christopher K, Kawashima, Agnieszka T, Lordén, Gema, Newton, Alexandra C, Nizet, Victor, Stender, Joshua D, Uchiyama, Satoshi   +7 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Roud table 1 - Summary: Biochemistry, cell and molecular biology

Memorias do Instituto Oswaldo Cruz, 1992
Luiz Pereira Silva, Joseph Schrevel
doaj   +1 more source

Unique metabolic regulation of micromeres contributes to gastrulation in the sea urchin embryo

Nature Communications
During development, a group of cells called organizers plays critical roles by sending signals to adjacent cells and controlling embryonic and tissue patterning.
Shakson Isaac, Douglas Dubosky, Ashley Waldron, Natsuko Emura, Aidan Furze, Kavya Rao, Masaru Mori, Ashok Ragavendran, Hideki Makinoshima, Mamiko Yajima   +9 more
doaj   +1 more source

Nuclear architecture and chromatin dynamics revealed by atomic force microscopy in combination with biochemistry and cell biology [PDF]

, 2008
Yasuhiro Hirano, Hirohide Takahashi, Masahiro Kumeta, Kohji Hizume, Yuya Hirai, Shotaro Otsuka, Shige H. Yoshimura, Kunio Takeyasu   +7 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

The debranching enzyme Dbr1 regulates lariat turnover and intron splicing

Nature Communications
The majority of genic transcription is intronic. Introns are removed by splicing as branched lariat RNAs which require rapid recycling. The branch site is recognized during splicing catalysis and later debranched by Dbr1 in the rate-limiting step of ...
Luke Buerer, Nathaniel E. Clark, Anastasia Welch, Chaorui Duan, Allison J. Taggart, Brittany A. Townley, Jing Wang, Rachel Soemedi, Stephen Rong, Chien-Ling Lin, Yi Zeng, Adam Katolik, Jonathan P. Staley, Masad J. Damha, Nima Mosammaparast, William G. Fairbrother   +15 more
doaj   +1 more source