Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The study of salivary amino acid profiles has attracted the attention of researchers, since amino acids are actively involved in most metabolic processes, including breast cancer.
Lyudmila V. Bel’skaya +2 more
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Soil Scientific Research Methods Used in Archaeology – Promising Soil Biochemistry: a Mini-review
This work seeks to review soil scientific methods that have been used and are still being used in archaeology. This review paper aims at emphasising the importance of soil science practice to archaeology thus adding a scientific analytical nature to the ...
Valerie Vranová +2 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Comparison of Lecture and Blended Teaching Methods on Learning and Satisfaction of Medical Students in Biochemistry Course [PDF]
Introduction: Considering the importance of biochemistry for medical students, its teaching methods are important. Using the appropriate teaching methods, teachers are trying to improve the effective learning and knowledge retention of students.
Mahvash Jafari
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Learning Difficulties in Biochemistry: Student Perspectives and Emerging Trends
This study analyzes students’ learning difficulties in understanding biochemistry concepts, materials, and processes through a survey, and examines bibliometric patterns of biochemistry learning models and methods to identify potential alternative ...
Siti Imroatus Sa'adah +5 more
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Students’ and Teachers’ Perceptions on Various Teaching-learning Methods of Competency-based Curriculum in Biochemistry [PDF]
Background: Competency-based Medical Education (CBME) is a learner-centered approach that emphasizes developing key competencies across cognitive, psychomotor, and affective domains. In 2019, India’s National Medical Commission (NMC) introduced CBME into
Rumi Deori, Monigopa Das
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The Catalytic Role of Glutamate 151 in the Leucine Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e [PDF]
Glutamate 151 has been proposed to act as the general acid/base during the peptide hydrolysis reaction catalyzed by the co-catalytic metallohydrolase from Aeromonas proteolytica (AAP).
Bzymek, Krzysztof P., Holz, Richard C.
core +1 more source

