Results 81 to 90 of about 434,338 (182)
Bioengineering 3D Pancreatic Cancer Models with Fibrotic Stroma for In Vitro Cancer Modeling
MicromachinesPancreatic ductal adenocarcinoma (PDAC) remains highly lethal due to late diagnosis, high malignancy, and profound resistance to therapy. Traditional two-dimensional (2D) cell cultures fail to recapitulate the complex tumor microenvironment (TME ...
Xingrun Lan, Keke Chen, Xiaoyun Wei
doaj +1 more source
Are short implants in the mandible safe? [PDF]
RGO: Revista Gaúcha de Odontologia, 2009 Objective: To analyze the importance of bioengineering and the improvement in surgical techniques demonstrated by the rates attained of the prevalence of successful placement of dental implants in the posterior region of the mandible, in D3 bone quality ...
Sergio Henrique Gonçalves Motta +4 more
doaj
Characterizing steady states of genome-scale metabolic networks in continuous cell cultures
, 2017 We present a model for continuous cell culture coupling intra-cellular metabolism to extracellular variables describing the state of the bioreactor, taking into account the growth capacity of the cell and the impact of toxic byproduct accumulation.
Fernandez-de-Cossio-Diaz, Jorge +2 more
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A perfusion culture system for assessing bone marrow stromal cell differentiation on PLGA scaffolds for bone repair [PDF]
, 2018 Biomaterials development for bone repair is currently hindered by the lack of physiologically relevant in vitro testing systems. Here we describe the novel use of a bi-directional perfusion bioreactor to support the long term culture of human bone marrow
Alini, Mauro +5 more
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Frontiers in Cell and Developmental BiologyThe optic nerve head (ONH) is a primary site of biomechanical strain within the eye. Here, tensile, compressive and shear forces can impact both physiologic function and pathologic dysfunction of the tissue.
Ana N. Strat +4 more
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Neural Regeneration ResearchSpinal cord injury results in the loss of sensory, motor, and autonomic functions, which almost always produces permanent physical disability. Thus, in the search for more effective treatments than those already applied for years, which are not entirely ...
Ana Milena Silva Olaya +3 more
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Journal of Extracellular VesiclesOuter membrane vesicles (OMVs) are nanosized vesicles naturally secreted by Gram‐negative bacteria and represent a promising platform for vaccine development.
Asja Garling +4 more
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Cavitation in Biological and Bioengineering Contexts [PDF]
, 2003 There are an increasing number of biological and bioengineering contexts in which cavitation is either utilized to create some desired effect or occurs as a byproduct of some other process.
Brennen, Christopher E.
core
Development of pathological skin models: from conventional techniques to 3D bioprinting
Frontiers in Bioengineering and BiotechnologyReconstructed human skin models were first developed in the 1970s. Since then, they have played a pivotal role in dermatological research, significantly advanced our understanding of skin biology, and brought huge insights into dermatological pathologies.
Maïté Rielland +5 more
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Production of Living Nanoparticles for Blood Cancer Therapy [PDF]
, 2018 Current cancer therapies leave much to be desired because they are very harmful to the patient and cause a significant decrease in quality of life. Chimeric Antigen Receptors (CAR) are a promising novel approach for treating specific types of leukemia ...
Mitchell, Peter +2 more
core +1 more source